Mouse fibroblasts A9 are deficient in HPRT and APRT

R. P. Cox, M. R. Krauss, M. E. Balis, J. Dancis

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


The A9 cell line, frequently used for cell hybridization, is deficient in both HPRT and APRT. Evidently the parent L cell line from which A9 was derived had previously undergone a spontaneous mutation to APRT deficiency. The double enzyme deficiency in A9 cells should be recognized by investigators who use this line for studies on somatic cell genetics.

Original languageEnglish (US)
Pages (from-to)272-273
Number of pages2
JournalAmerican Journal of Human Genetics
Issue number2
StatePublished - Jan 1 1974

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)


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