Motion-compensated reconstruction for limited-angle multiphase cardiac CT

Mingwu Jin, Cong Zhao, Xun Jia, Lifeng Yu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations


ECG-gated multiphase cardiac CT (MP-CCT) is free of motion artifacts and can provide the extra information of cardiac functions for the diagnosis of coronary artery disease. Used majority as a screening tool, the excessive radiation dose becomes a concern of MP-CCT. In this work, we propose a motion-compensated reconstruction method for MP-CCT with the limited angle acquisition for each phase in order to substantially reduce the radiation dose. MP-CCT of the XCAT phantom with eight cardiac phases was simulated with 90° coverage for each phase. The motion was estimated from images reconstructed by combining projections from two phases (for a full 180° coverage). To reconstruct the image at phase k, the motion fields were used to warp images at phase k to phase j (j = 1∼8 and j ≠ k) so that all projection data could be used for a total variation (TV) constrained reconstruction. The results show that TV reconstruction for each cardiac phase independently (TV-Single Phase) suffered severe limited-angle artifacts. TV reconstruction with two-phase projections (TV-Two Phases) improved the image quality and was suitable for good motion estimation. Motion-compensated TV reconstruction (TV-MC) achieved almost artifact-free images, although some motion errors could be seen. The root mean square error values are 254 HU, 64 HU and 47 HU for TV-Single Phase, TV-Two Phases, and TV-MC, respectively.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2018
Subtitle of host publicationPhysics of Medical Imaging
EditorsTaly Gilat Schmidt, Guang-Hong Chen, Joseph Y. Lo
ISBN (Electronic)9781510616356
StatePublished - 2018
EventMedical Imaging 2018: Physics of Medical Imaging - Houston, United States
Duration: Feb 12 2018Feb 15 2018

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


OtherMedical Imaging 2018: Physics of Medical Imaging
Country/TerritoryUnited States


  • Multiphase cardiac CT (MP-CCT)
  • limited angle acquisition
  • motion-compensated reconstruction
  • radiation dose reduction

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging


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