TY - JOUR
T1 - Morphea
T2 - Current concepts
AU - Florez-Pollack, Stephanie
AU - Kunzler, Elaine
AU - Jacobe, Heidi T.
N1 - Publisher Copyright:
© 2018
PY - 2018/7/1
Y1 - 2018/7/1
N2 - Morphea is an inflammatory, sclerosing skin disorder that can involve the underlying soft tissues. Although the cause of morphea remains poorly investigated, genetic predisposition, immune dysregulation, and environmental factors have been implicated. Morphea is associated with cosmetic and functional sequelae, and internal organ involvement is rare. Early diagnosis and treatment are imperative to minimize damage such as limitation of range of motion. This review summarizes advances in diagnosis and treatment of morphea, allowing clinicians to better serve patients with this condition.
AB - Morphea is an inflammatory, sclerosing skin disorder that can involve the underlying soft tissues. Although the cause of morphea remains poorly investigated, genetic predisposition, immune dysregulation, and environmental factors have been implicated. Morphea is associated with cosmetic and functional sequelae, and internal organ involvement is rare. Early diagnosis and treatment are imperative to minimize damage such as limitation of range of motion. This review summarizes advances in diagnosis and treatment of morphea, allowing clinicians to better serve patients with this condition.
UR - http://www.scopus.com/inward/record.url?scp=85049434708&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85049434708&partnerID=8YFLogxK
U2 - 10.1016/j.clindermatol.2018.04.005
DO - 10.1016/j.clindermatol.2018.04.005
M3 - Article
C2 - 30047431
AN - SCOPUS:85049434708
SN - 0738-081X
VL - 36
SP - 475
EP - 486
JO - Clinics in Dermatology
JF - Clinics in Dermatology
IS - 4
ER -