TY - JOUR
T1 - Midaortic syndrome in the fetus and premature newborn
T2 - A new etiology of nonimmune hydrops fetalis and reversible fetal cardiomyopathy
AU - Zeltser, Ilana
AU - Parness, Ira A.
AU - Ko, Helen
AU - Holzman, Ian R.
AU - Kamenir, Steven A.
PY - 2003/6/1
Y1 - 2003/6/1
N2 - Nonimmune hydrops fetalis is the final common pathway of many conditions that ultimately result in fetal anasarca. Even after extensive evaluation, the etiology of a small percentage of cases of hydrops remains unknown. We present a case of midaortic syndrome, also known as abdominal coarctation syndrome, in a fetus with hydrops and a severe cardiomyopathy. The clinical manifestations of midaortic syndrome in this fetus and premature newborn, including malignant hypertension and reversible cardiomyopathy, are detailed. The fetal pathophysiology of midaortic syndrome remains speculative, but likely includes fetal hypertension as the cause of cardiac dysfunction. To our knowledge, this is the first report of midaortic syndrome as an etiology for nonimmune hydrops fetalis.
AB - Nonimmune hydrops fetalis is the final common pathway of many conditions that ultimately result in fetal anasarca. Even after extensive evaluation, the etiology of a small percentage of cases of hydrops remains unknown. We present a case of midaortic syndrome, also known as abdominal coarctation syndrome, in a fetus with hydrops and a severe cardiomyopathy. The clinical manifestations of midaortic syndrome in this fetus and premature newborn, including malignant hypertension and reversible cardiomyopathy, are detailed. The fetal pathophysiology of midaortic syndrome remains speculative, but likely includes fetal hypertension as the cause of cardiac dysfunction. To our knowledge, this is the first report of midaortic syndrome as an etiology for nonimmune hydrops fetalis.
KW - Abdominal coarctation
KW - Fetal cardiomyopathy
KW - Hydrops fetalis
KW - Midaortic syndrome
KW - Renal artery stenosis
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UR - http://www.scopus.com/inward/citedby.url?scp=0038312158&partnerID=8YFLogxK
U2 - 10.1542/peds.111.6.1437
DO - 10.1542/peds.111.6.1437
M3 - Article
C2 - 12777568
AN - SCOPUS:0038312158
SN - 0031-4005
VL - 111
SP - 1437
EP - 1442
JO - Pediatrics
JF - Pediatrics
IS - 6 I
ER -