The synthesis of benzo[b][1,4]thiazin-3(4H)-one derivatives in a simple and efficient method from the one-pot reaction of substituted 2-chlorobenzenthiols, chloroacetyl chloride, and primary amines via Smiles rearrangement under microwave irradiation gave high yields (65-92%) of the products with short reaction time (15-20 min).
|Original language||English (US)|
|Number of pages||6|
|State||Published - Oct 6 2008|
- Smiles rearrangement
ASJC Scopus subject areas
- Drug Discovery
- Organic Chemistry