TY - JOUR
T1 - Microvilli and cell-cell fusion during fertilization
AU - Wilson, Nedra F.
AU - Snell, William J.
PY - 1998/3
Y1 - 1998/3
N2 - A number of fundamental biological processes, ranging from fertilization and embryonic development to viral infection, depend upon a complex interplay between cells that results in the fusion of their plasma membranes. Surprisingly, the cellular and molecular mechanisms underlying cell-cell fusion remain largely unknown. Here, the authors discuss evidence suggesting that microvilli play a central role in fusion of many cells and present features of these actin-filled, a cell-surface protrusions that might make them particularly well suited as cell-fusion organelles.
AB - A number of fundamental biological processes, ranging from fertilization and embryonic development to viral infection, depend upon a complex interplay between cells that results in the fusion of their plasma membranes. Surprisingly, the cellular and molecular mechanisms underlying cell-cell fusion remain largely unknown. Here, the authors discuss evidence suggesting that microvilli play a central role in fusion of many cells and present features of these actin-filled, a cell-surface protrusions that might make them particularly well suited as cell-fusion organelles.
UR - http://www.scopus.com/inward/record.url?scp=0032030639&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032030639&partnerID=8YFLogxK
U2 - 10.1016/S0962-8924(98)01234-3
DO - 10.1016/S0962-8924(98)01234-3
M3 - Article
C2 - 9695816
AN - SCOPUS:0032030639
SN - 0962-8924
VL - 8
SP - 93
EP - 96
JO - Trends in Cell Biology
JF - Trends in Cell Biology
IS - 3
ER -