Microvascular free tissue reconstruction in the patient with multiple courses of radiation

Eli A. Gordin, Yadranko Ducic

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Objectives/Hypothesis: To assess the feasibility of microvascular free tissue transfer in the multiply irradiated patient. Study Design: Retrospective cohort analysis of 48 patients in a tertiary care, private practice setting. Methods: Inclusion criteria were defined as patients who received multiple courses of radiation and underwent subsequent free tissue reconstruction to manage treatment-related complications (n = 24) or defects following additional oncologic surgery (n = 24). The main outcome measures included total and partial flap necrosis, hardware exposure, and pharyngocutaneous fistula. The minimum follow-up was 6 months. Results: One case of total flap failure, two cases of partial skin paddle necrosis, one case of poor wound healing of the surrounding tissue to the flap, six cases of hardware exposure, 11 cases of fistula with eight requiring operative intervention, three cases requiring and additional free flap to supplement reconstruction, and one stroke. Conclusions: Microvascular free tissue transfer to the head and neck is expected to provide a successful reconstruction in patients who have received multiple courses of radiation and who develop second primary tumors, recurrence of disease, or who suffer from late complications of their radiation therapy.

Original languageEnglish (US)
Pages (from-to)2252-2256
Number of pages5
Issue number10
StatePublished - Oct 1 2014


  • Complications of radiation therapy
  • Microvascular free tissue transfer
  • Pharyngocutaneous fistula
  • Radionecrosis

ASJC Scopus subject areas

  • Otorhinolaryngology


Dive into the research topics of 'Microvascular free tissue reconstruction in the patient with multiple courses of radiation'. Together they form a unique fingerprint.

Cite this