Micromachined nanoporous membranes for blood oxygenation systems

Vijayakrishnan Ambravaneswaran; Susheil Uttamaraj; Zeynep Çelik-Butler; Robert C. Eberhart; Charles J. Chuong; Richard E. Billo; Michael A. Savitt

doi:10.1109/NANO.2008.66

Micromachined nanoporous membranes for blood oxygenation systems

Vijayakrishnan Ambravaneswaran, Susheil Uttamaraj, Zeynep Çelik-Butler, Robert C. Eberhart, Charles J. Chuong, Richard E. Billo, Michael A. Savitt

Surgery

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

3 Scopus citations

Abstract

Nanostructured membranes with precisely engineered nanopores were fabricated on a thin silicon nitride membrane, using a combination of bulk micromachining and focused-ion-beam drilling. These membranes are designed to preserve microscale blood channel dimensions, thereby permitting the red cell shape change that enhances gas exchange in the pulmonary capillary. The membranes were tested for their mechanical stability and the results were verified with finite element analysis. Initial studies have proven the membranes to be robust, and capable of withstanding pressures typically experienced in blood oxygenator channels. A novel MEMS-based blood oxygenation system employing the nanoporous membranes is also presented. The oxygenation system is designed to have controlled blood and gas volumes for efficient blood oxygenation.

Original language	English (US)
Title of host publication	2008 8th IEEE Conference on Nanotechnology, IEEE-NANO
Publisher	IEEE Computer Society
Pages	201-204
Number of pages	4
ISBN (Print)	9781424421046
DOIs	https://doi.org/10.1109/NANO.2008.66
State	Published - 2008
Event	2008 8th IEEE Conference on Nanotechnology, IEEE-NANO - Arlington, TX, United States Duration: Aug 18 2008 → Aug 21 2008

Publication series

Name	2008 8th IEEE Conference on Nanotechnology, IEEE-NANO

Other

Other	2008 8th IEEE Conference on Nanotechnology, IEEE-NANO
Country/Territory	United States
City	Arlington, TX
Period	8/18/08 → 8/21/08

ASJC Scopus subject areas

Management, Monitoring, Policy and Law
Renewable Energy, Sustainability and the Environment
General Energy
Energy Engineering and Power Technology
Modeling and Simulation
Electrical and Electronic Engineering
Fuel Technology

Access to Document

10.1109/NANO.2008.66

Cite this

Ambravaneswaran, V., Uttamaraj, S., Çelik-Butler, Z., Eberhart, R. C., Chuong, C. J., Billo, R. E., & Savitt, M. A. (2008). Micromachined nanoporous membranes for blood oxygenation systems. In 2008 8th IEEE Conference on Nanotechnology, IEEE-NANO (pp. 201-204). Article 4617048 (2008 8th IEEE Conference on Nanotechnology, IEEE-NANO). IEEE Computer Society. https://doi.org/10.1109/NANO.2008.66

Micromachined nanoporous membranes for blood oxygenation systems. / Ambravaneswaran, Vijayakrishnan; Uttamaraj, Susheil; Çelik-Butler, Zeynep et al.
2008 8th IEEE Conference on Nanotechnology, IEEE-NANO. IEEE Computer Society, 2008. p. 201-204 4617048 (2008 8th IEEE Conference on Nanotechnology, IEEE-NANO).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Ambravaneswaran, V, Uttamaraj, S, Çelik-Butler, Z, Eberhart, RC, Chuong, CJ, Billo, RE & Savitt, MA 2008, Micromachined nanoporous membranes for blood oxygenation systems. in 2008 8th IEEE Conference on Nanotechnology, IEEE-NANO., 4617048, 2008 8th IEEE Conference on Nanotechnology, IEEE-NANO, IEEE Computer Society, pp. 201-204, 2008 8th IEEE Conference on Nanotechnology, IEEE-NANO, Arlington, TX, United States, 8/18/08. https://doi.org/10.1109/NANO.2008.66

@inproceedings{bd31b807e7e04e2c8f80865d4e4d8a46,

title = "Micromachined nanoporous membranes for blood oxygenation systems",

abstract = "Nanostructured membranes with precisely engineered nanopores were fabricated on a thin silicon nitride membrane, using a combination of bulk micromachining and focused-ion-beam drilling. These membranes are designed to preserve microscale blood channel dimensions, thereby permitting the red cell shape change that enhances gas exchange in the pulmonary capillary. The membranes were tested for their mechanical stability and the results were verified with finite element analysis. Initial studies have proven the membranes to be robust, and capable of withstanding pressures typically experienced in blood oxygenator channels. A novel MEMS-based blood oxygenation system employing the nanoporous membranes is also presented. The oxygenation system is designed to have controlled blood and gas volumes for efficient blood oxygenation.",

author = "Vijayakrishnan Ambravaneswaran and Susheil Uttamaraj and Zeynep {\c C}elik-Butler and Eberhart, {Robert C.} and Chuong, {Charles J.} and Billo, {Richard E.} and Savitt, {Michael A.}",

year = "2008",

doi = "10.1109/NANO.2008.66",

language = "English (US)",

isbn = "9781424421046",

series = "2008 8th IEEE Conference on Nanotechnology, IEEE-NANO",

publisher = "IEEE Computer Society",

pages = "201--204",

booktitle = "2008 8th IEEE Conference on Nanotechnology, IEEE-NANO",

note = "2008 8th IEEE Conference on Nanotechnology, IEEE-NANO ; Conference date: 18-08-2008 Through 21-08-2008",

}

TY - GEN

T1 - Micromachined nanoporous membranes for blood oxygenation systems

AU - Ambravaneswaran, Vijayakrishnan

AU - Uttamaraj, Susheil

AU - Çelik-Butler, Zeynep

AU - Eberhart, Robert C.

AU - Chuong, Charles J.

AU - Billo, Richard E.

AU - Savitt, Michael A.

PY - 2008

Y1 - 2008

N2 - Nanostructured membranes with precisely engineered nanopores were fabricated on a thin silicon nitride membrane, using a combination of bulk micromachining and focused-ion-beam drilling. These membranes are designed to preserve microscale blood channel dimensions, thereby permitting the red cell shape change that enhances gas exchange in the pulmonary capillary. The membranes were tested for their mechanical stability and the results were verified with finite element analysis. Initial studies have proven the membranes to be robust, and capable of withstanding pressures typically experienced in blood oxygenator channels. A novel MEMS-based blood oxygenation system employing the nanoporous membranes is also presented. The oxygenation system is designed to have controlled blood and gas volumes for efficient blood oxygenation.

AB - Nanostructured membranes with precisely engineered nanopores were fabricated on a thin silicon nitride membrane, using a combination of bulk micromachining and focused-ion-beam drilling. These membranes are designed to preserve microscale blood channel dimensions, thereby permitting the red cell shape change that enhances gas exchange in the pulmonary capillary. The membranes were tested for their mechanical stability and the results were verified with finite element analysis. Initial studies have proven the membranes to be robust, and capable of withstanding pressures typically experienced in blood oxygenator channels. A novel MEMS-based blood oxygenation system employing the nanoporous membranes is also presented. The oxygenation system is designed to have controlled blood and gas volumes for efficient blood oxygenation.

UR - http://www.scopus.com/inward/record.url?scp=55349109294&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=55349109294&partnerID=8YFLogxK

U2 - 10.1109/NANO.2008.66

DO - 10.1109/NANO.2008.66

M3 - Conference contribution

AN - SCOPUS:55349109294

SN - 9781424421046

T3 - 2008 8th IEEE Conference on Nanotechnology, IEEE-NANO

SP - 201

EP - 204

BT - 2008 8th IEEE Conference on Nanotechnology, IEEE-NANO

PB - IEEE Computer Society

T2 - 2008 8th IEEE Conference on Nanotechnology, IEEE-NANO

Y2 - 18 August 2008 through 21 August 2008

ER -

Micromachined nanoporous membranes for blood oxygenation systems

Abstract

Publication series

Other

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this