Metformin for the treatment of polycystic ovary syndrome (PCOS)

Satin S. Patel; Victor E. Beshay; Bruce R. Carr

doi:10.1007/978-1-60327-392-3_2

Metformin for the treatment of polycystic ovary syndrome (PCOS)

Satin S. Patel, Victor E. Beshay, Bruce R. Carr

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Because of the high prevalence of insulin resistance, there is a growing interest in the application of insulin sensitizing agents in patients with polycystic ovary syndrome (PCOS). Metformin is the most widely prescribed insulin sensitizing agent in patients with PCOS. In this chapter, we address the importance of lifestyle modification as the initial intervention in patients with PCOS. Furthermore, we discuss the efficacy of metformin compared to low-dose estrogen/progestin oral contraceptives in restoring menstrual cyclicity, reducing androgen excess, and protecting against uterine malignancies. Additionally, the role of metformin in PCOS patients with infertility is addressed.

Original language	English (US)
Title of host publication	Biennial Review of Infertility
Subtitle of host publication	Volume 1
Publisher	Humana Press
Pages	21-28
Number of pages	8
ISBN (Print)	9781603273916
DOIs	https://doi.org/10.1007/978-1-60327-392-3_2
State	Published - Dec 1 2009

Keywords

Androgen
Anovulation
Hyperinsulinemia
Metformin
PCOS
Polycystic ovary syndrome

ASJC Scopus subject areas

Medicine(all)

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10.1007/978-1-60327-392-3_2

Cite this

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abstract = "Because of the high prevalence of insulin resistance, there is a growing interest in the application of insulin sensitizing agents in patients with polycystic ovary syndrome (PCOS). Metformin is the most widely prescribed insulin sensitizing agent in patients with PCOS. In this chapter, we address the importance of lifestyle modification as the initial intervention in patients with PCOS. Furthermore, we discuss the efficacy of metformin compared to low-dose estrogen/progestin oral contraceptives in restoring menstrual cyclicity, reducing androgen excess, and protecting against uterine malignancies. Additionally, the role of metformin in PCOS patients with infertility is addressed.",

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Metformin for the treatment of polycystic ovary syndrome (PCOS)

Abstract

Keywords

ASJC Scopus subject areas

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