Meta-analysis of randomized clinical trials of finasteride

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21 Scopus citations


A meta-analysis was recently published based on six randomized clinical trials of at least one year duration involving finasteride 5 mg and placebo in the treatment of men with clinical benign prostatic hyperplasia (BPH). In a pooled analysis, mean improvement in symptoms and urinary flow rate with finasteride were found to increase with increasing prostate size. This article reviews the previous publication of this meta-analysis, which indicated prostate volume is a key predictor of outcomes with finasteride treatment and suggested that finasteride is most effective in men with large prostates.

Original languageEnglish (US)
Pages (from-to)46-49
Number of pages4
Issue number4 SUPPL. A
StatePublished - Apr 1 1998

ASJC Scopus subject areas

  • Urology


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