MEN2B Masquerading as Postural Orthostatic Tachycardia Syndrome

Ghazi Khan; John Giacona; Sasan Mirfakhraee; Steven Vernino; Wanpen Vongpatanasin

doi:10.1016/j.jaccas.2022.04.009

MEN2B Masquerading as Postural Orthostatic Tachycardia Syndrome

Ghazi Khan, John Giacona, Sasan Mirfakhraee, Steven Vernino, Wanpen Vongpatanasin

Research output: Contribution to journal › Article › peer-review

Abstract

Multiple endocrine neoplasia type 2B is a genetic disorder characterized by pheochromocytoma, medullary thyroid carcinoma, and marfanoid features. Although hypertension and stress cardiomyopathy are known cardiovascular complications of pheochromocytoma, clinical presentation maybe subtle. Elevation in heart rate and lightheadedness induced by catecholamine excess may mimic clinical features of postural orthostatic tachycardia syndrome, as shown in our case report. (Level of Difficulty: Advanced.)

Original language	English (US)
Pages (from-to)	814-818
Number of pages	5
Journal	JACC: Case Reports
Volume	4
Issue number	13
DOIs	https://doi.org/10.1016/j.jaccas.2022.04.009
State	Published - Jul 6 2022

Keywords

awareness
cancer
cardiomyopathy
genetic disorders
hypertension
tachycardia

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1016/j.jaccas.2022.04.009

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abstract = "Multiple endocrine neoplasia type 2B is a genetic disorder characterized by pheochromocytoma, medullary thyroid carcinoma, and marfanoid features. Although hypertension and stress cardiomyopathy are known cardiovascular complications of pheochromocytoma, clinical presentation maybe subtle. Elevation in heart rate and lightheadedness induced by catecholamine excess may mimic clinical features of postural orthostatic tachycardia syndrome, as shown in our case report. (Level of Difficulty: Advanced.)",

keywords = "awareness, cancer, cardiomyopathy, genetic disorders, hypertension, tachycardia",

author = "Ghazi Khan and John Giacona and Sasan Mirfakhraee and Steven Vernino and Wanpen Vongpatanasin",

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AU - Mirfakhraee, Sasan

AU - Vernino, Steven

AU - Vongpatanasin, Wanpen

PY - 2022/7/6

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AB - Multiple endocrine neoplasia type 2B is a genetic disorder characterized by pheochromocytoma, medullary thyroid carcinoma, and marfanoid features. Although hypertension and stress cardiomyopathy are known cardiovascular complications of pheochromocytoma, clinical presentation maybe subtle. Elevation in heart rate and lightheadedness induced by catecholamine excess may mimic clinical features of postural orthostatic tachycardia syndrome, as shown in our case report. (Level of Difficulty: Advanced.)

KW - awareness

KW - cancer

KW - cardiomyopathy

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KW - hypertension

KW - tachycardia

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MEN2B Masquerading as Postural Orthostatic Tachycardia Syndrome

Abstract

Keywords

ASJC Scopus subject areas

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