Membrane protein structure predictions for exploration

Nick V. Grishin

doi:10.1016/j.cell.2012.06.004

Membrane protein structure predictions for exploration

Research output: Contribution to journal › Short survey › peer-review

Abstract

A daring experiment is performed. Using sequence alignments to predict contacts between residues in protein spatial structures, Hopf et al. are publishing untested de novo structure models for 11 transmembrane protein families. Will their models stand the test of time and hold up to experimentation? The prospects are excellent.

Original language	English (US)
Pages (from-to)	1424-1425
Number of pages	2
Journal	Cell
Volume	149
Issue number	7
DOIs	https://doi.org/10.1016/j.cell.2012.06.004
State	Published - Jun 22 2012

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

Access to Document

10.1016/j.cell.2012.06.004

Cite this

@article{46551ab50c6b47dcb234cbbbb98e4de7,

title = "Membrane protein structure predictions for exploration",

abstract = "A daring experiment is performed. Using sequence alignments to predict contacts between residues in protein spatial structures, Hopf et al. are publishing untested de novo structure models for 11 transmembrane protein families. Will their models stand the test of time and hold up to experimentation? The prospects are excellent.",

author = "Grishin, {Nick V.}",

note = "Funding Information: This work was supported, in part, by the National Institutes of Health (GM094575 to N.V.G.) and the Welch Foundation (I-1505 to N.V.G.).",

year = "2012",

month = jun,

day = "22",

doi = "10.1016/j.cell.2012.06.004",

language = "English (US)",

volume = "149",

pages = "1424--1425",

journal = "Cell",

issn = "0092-8674",

publisher = "Cell Press",

number = "7",

}

TY - JOUR

T1 - Membrane protein structure predictions for exploration

AU - Grishin, Nick V.

N1 - Funding Information: This work was supported, in part, by the National Institutes of Health (GM094575 to N.V.G.) and the Welch Foundation (I-1505 to N.V.G.).

PY - 2012/6/22

Y1 - 2012/6/22

N2 - A daring experiment is performed. Using sequence alignments to predict contacts between residues in protein spatial structures, Hopf et al. are publishing untested de novo structure models for 11 transmembrane protein families. Will their models stand the test of time and hold up to experimentation? The prospects are excellent.

AB - A daring experiment is performed. Using sequence alignments to predict contacts between residues in protein spatial structures, Hopf et al. are publishing untested de novo structure models for 11 transmembrane protein families. Will their models stand the test of time and hold up to experimentation? The prospects are excellent.

UR - http://www.scopus.com/inward/record.url?scp=84862699426&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84862699426&partnerID=8YFLogxK

U2 - 10.1016/j.cell.2012.06.004

DO - 10.1016/j.cell.2012.06.004

M3 - Short survey

C2 - 22726429

AN - SCOPUS:84862699426

SN - 0092-8674

VL - 149

SP - 1424

EP - 1425

JO - Cell

JF - Cell

IS - 7

ER -

Membrane protein structure predictions for exploration

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this