Medications for constipation in 2020

Ricardo Medina-Centeno

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations


Purpose of reviewChronic constipation is a common problem that substantially impacts the quality of life of patients and families, healthcare professionals, and resources. The purpose of this review is to discuss the medications that are available for management of chronic constipation, including medications that have been approved by the FDA for adults, other been studied in pediatrics now, and might become available within the upcoming years.Recent findingsRecent developments in the evaluation of childhood constipation are providing a better understanding into defecation disorders in children and not only new therapies are becoming available, including medications, but also other therapies, such as biofeedback for treatment of functional defecation disorders, electrical stimulation, and surgeries. The aim of this article is to provide an update on the medications that are available for management of chronic constipation, especially with the development and study of newer medications, such as Linaclotide and Lubiprostone with promising results in both adult and pediatric patients.SummaryThis review will help us identify and have a better understanding regarding what medications are available for use and the indications, so that we can better manage patients with chronic constipation.Video abstract

Original languageEnglish (US)
Pages (from-to)668-673
Number of pages6
JournalCurrent opinion in pediatrics
Issue number5
StatePublished - Oct 1 2020


  • linaclotide
  • lubiprostone
  • osmotic laxatives
  • stimulant laxatives

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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