Medical hyperspectral imaging: A review

Guolan Lu, Baowei Fei

Research output: Contribution to journalArticlepeer-review

1461 Scopus citations


Hyperspectral imaging (HSI) is an emerging imaging modality for medical applications, especially in disease diagnosis and image-guided surgery. HSI acquires a three-dimensional dataset called hypercube, with two spatial dimensions and one spectral dimension. Spatially resolved spectral imaging obtained by HSI provides diagnostic information about the tissue physiology, morphology, and composition. This review paper presents an overview of the literature on medical hyperspectral imaging technology and its applications. The aim of the survey is threefold: an introduction for those new to the field, an overview for those working in the field, and a reference for those searching for literature on a specific application.

Original languageEnglish (US)
Article number010901
JournalJournal of biomedical optics
Issue number1
StatePublished - Jan 2014
Externally publishedYes


  • Cancer detection and diagnosis
  • Image analysis and classification
  • Image-guided surgery
  • Medical hyperspectral imaging
  • Quantitative imaging
  • Tissue optics

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Biomedical Engineering


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