Mechanisms of Homeostatically Regulated Behaviors

Joel K. Elmquist; Jeffrey M. Zigman; Clifford B. Saper

doi:10.1007/978-3-030-88832-9_62

Mechanisms of Homeostatically Regulated Behaviors

Joel K. Elmquist, Jeffrey M. Zigman, Clifford B. Saper

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Homeostasis is broadly defined as the maintenance of internal physiological conditions in the face of altered environmental conditions. Conditions which are normally homeostatically maintained include body weight, blood glucose, body temperature, sleep, and thyroid hormone economy, among others. In this chapter, we outline some basic concepts of the anatomy and function of the hypothalamus, which is often viewed as the master regulator of homeostatic control. In addition, we highlight the hypothalamic regulation of food intake, energy balance, and metabolism, as well as hypothalamic regulation of thyroid function and autonomic function as prototypical examples of how the hypothalamic can respond to changing environmental conditions resulting in a coordinated set of responses.

Original language	English (US)
Title of host publication	Neuroscience in the 21st Century
Subtitle of host publication	From Basic to Clinical: Third Edition
Publisher	Springer International Publishing
Pages	2415-2443
Number of pages	29
ISBN (Electronic)	9783030888329
ISBN (Print)	9783030888312
DOIs	https://doi.org/10.1007/978-3-030-88832-9_62
State	Published - Jan 1 2022

Keywords

Agouti-related protein (AgRP)
Autonomic function
Ghrelin
Homeostasis. See also Hypothalamus
Hyperthyroidism
Hypocretin
Hypothalamus
Leptin
Medial forebrain bundle
Neurohypophysis
Nissl staining
Plasma ghrelin
Prader-Willi Syndrome
Prevalent model of energy balance
Pro-opiomelanocortin neurons (POMC)
Tanycytes
Thyroid hormone
Thyroid-stimulating hormone

ASJC Scopus subject areas

General Medicine
General Neuroscience

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10.1007/978-3-030-88832-9_62

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title = "Mechanisms of Homeostatically Regulated Behaviors",

abstract = "Homeostasis is broadly defined as the maintenance of internal physiological conditions in the face of altered environmental conditions. Conditions which are normally homeostatically maintained include body weight, blood glucose, body temperature, sleep, and thyroid hormone economy, among others. In this chapter, we outline some basic concepts of the anatomy and function of the hypothalamus, which is often viewed as the master regulator of homeostatic control. In addition, we highlight the hypothalamic regulation of food intake, energy balance, and metabolism, as well as hypothalamic regulation of thyroid function and autonomic function as prototypical examples of how the hypothalamic can respond to changing environmental conditions resulting in a coordinated set of responses.",

keywords = "Agouti-related protein (AgRP), Autonomic function, Ghrelin, Homeostasis. See also Hypothalamus, Hyperthyroidism, Hypocretin, Hypothalamus, Leptin, Medial forebrain bundle, Neurohypophysis, Nissl staining, Plasma ghrelin, Prader-Willi Syndrome, Prevalent model of energy balance, Pro-opiomelanocortin neurons (POMC), Tanycytes, Thyroid hormone, Thyroid-stimulating hormone",

author = "Elmquist, {Joel K.} and Zigman, {Jeffrey M.} and Saper, {Clifford B.}",

note = "Publisher Copyright: {\textcopyright} Springer Science+Business Media New York 2013, 2016 and Springer Nature Switzerland AG 2022.",

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doi = "10.1007/978-3-030-88832-9_62",

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AU - Elmquist, Joel K.

AU - Zigman, Jeffrey M.

AU - Saper, Clifford B.

N1 - Publisher Copyright: © Springer Science+Business Media New York 2013, 2016 and Springer Nature Switzerland AG 2022.

PY - 2022/1/1

Y1 - 2022/1/1

N2 - Homeostasis is broadly defined as the maintenance of internal physiological conditions in the face of altered environmental conditions. Conditions which are normally homeostatically maintained include body weight, blood glucose, body temperature, sleep, and thyroid hormone economy, among others. In this chapter, we outline some basic concepts of the anatomy and function of the hypothalamus, which is often viewed as the master regulator of homeostatic control. In addition, we highlight the hypothalamic regulation of food intake, energy balance, and metabolism, as well as hypothalamic regulation of thyroid function and autonomic function as prototypical examples of how the hypothalamic can respond to changing environmental conditions resulting in a coordinated set of responses.

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KW - Agouti-related protein (AgRP)

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KW - Homeostasis. See also Hypothalamus

KW - Hyperthyroidism

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KW - Hypothalamus

KW - Leptin

KW - Medial forebrain bundle

KW - Neurohypophysis

KW - Nissl staining

KW - Plasma ghrelin

KW - Prader-Willi Syndrome

KW - Prevalent model of energy balance

KW - Pro-opiomelanocortin neurons (POMC)

KW - Tanycytes

KW - Thyroid hormone

KW - Thyroid-stimulating hormone

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ER -

Mechanisms of Homeostatically Regulated Behaviors

Abstract

Keywords

ASJC Scopus subject areas

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