TY - JOUR
T1 - Mechanical ventilation and middle ear effusions among tracheostomy-dependent children
AU - Wynings, Erin M.
AU - Jaffal, Hussein
AU - St. John, Rachel
AU - Johnson, Romaine F.
AU - Chorney, Stephen R.
N1 - Publisher Copyright:
© 2022 Elsevier B.V.
PY - 2022/4
Y1 - 2022/4
N2 - Objective: To determine the cumulative 24-month incidence of middle ear effusion (MEE) among tracheostomy-dependent children requiring ventilatory support. Methods: A prospective longitudinal cohort study included all children under 2 years of age with a tracheostomy placed at a tertiary care children's hospital between 2015 and 2020 that obtained at least one tympanometry exam. The development of MEE, defined as a flat tympanogram with normal external canal volume, and mechanical ventilation requirement at examination were recorded. Results: Ninety-four children with a mean age at tracheostomy of 5.4 months (SD: 3.7) were included. During a mean follow-up of 18.3 months (SD: 14.6) (median: 14.1 months, interquartile range: 6.6–27.8), 192 tympanometry examinations were obtained with 59% (114/192) while requiring mechanical ventilation. Within 24 months after tracheostomy, 56.5% (95% CI: 48.9–64.4%) of children developed at least one MEE. Among those on mechanical ventilation, 74.0% (95% CI: 65.6–82.5%) developed MEE compared to 31.2% (95% CI: 21.4–44.0%) not on mechanical ventilation (HR: 2.97, 95% CI: 1.46–6.05, P = .003). A persistent MEE on two consecutive exams was not statistically more common for children on a ventilator (OR: 0.64, 95% CI: 0.01–6.95, P = .70). When controlling for age at exam, craniofacial syndrome, and newborn hearing test results on logistic regression, ventilator-dependence significantly predicted the presence of MEE (OR: 2.34, 95% CI: 1.18–4.68, P = .02). Conclusion: Children with a tracheostomy were more likely to develop MEE when requiring mechanical ventilation. Clinicians should recognize this risk factor and appropriately assess for development of MEE to mitigate adverse speech and language development outcomes in this vulnerable population.
AB - Objective: To determine the cumulative 24-month incidence of middle ear effusion (MEE) among tracheostomy-dependent children requiring ventilatory support. Methods: A prospective longitudinal cohort study included all children under 2 years of age with a tracheostomy placed at a tertiary care children's hospital between 2015 and 2020 that obtained at least one tympanometry exam. The development of MEE, defined as a flat tympanogram with normal external canal volume, and mechanical ventilation requirement at examination were recorded. Results: Ninety-four children with a mean age at tracheostomy of 5.4 months (SD: 3.7) were included. During a mean follow-up of 18.3 months (SD: 14.6) (median: 14.1 months, interquartile range: 6.6–27.8), 192 tympanometry examinations were obtained with 59% (114/192) while requiring mechanical ventilation. Within 24 months after tracheostomy, 56.5% (95% CI: 48.9–64.4%) of children developed at least one MEE. Among those on mechanical ventilation, 74.0% (95% CI: 65.6–82.5%) developed MEE compared to 31.2% (95% CI: 21.4–44.0%) not on mechanical ventilation (HR: 2.97, 95% CI: 1.46–6.05, P = .003). A persistent MEE on two consecutive exams was not statistically more common for children on a ventilator (OR: 0.64, 95% CI: 0.01–6.95, P = .70). When controlling for age at exam, craniofacial syndrome, and newborn hearing test results on logistic regression, ventilator-dependence significantly predicted the presence of MEE (OR: 2.34, 95% CI: 1.18–4.68, P = .02). Conclusion: Children with a tracheostomy were more likely to develop MEE when requiring mechanical ventilation. Clinicians should recognize this risk factor and appropriately assess for development of MEE to mitigate adverse speech and language development outcomes in this vulnerable population.
KW - Mechanical ventilation
KW - Middle ear effusion
KW - Otitis media with effusion
KW - Pediatric tracheostomy
KW - Tympanometry
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U2 - 10.1016/j.ijporl.2022.111062
DO - 10.1016/j.ijporl.2022.111062
M3 - Article
C2 - 35202901
AN - SCOPUS:85124894822
SN - 0165-5876
VL - 155
JO - International Journal of Pediatric Otorhinolaryngology
JF - International Journal of Pediatric Otorhinolaryngology
M1 - 111062
ER -