Macroscopic and microscopic imaging modalities for diagnosis and monitoring of urogenital schistosomiasis

Shelly Xie, Eglal Shalaby-Rana, Austin Hester, Jared Honeycutt, Chi Ling Fu, Deborah Boyett, Wen Jiang, Michael H. Hsieh

Research output: Chapter in Book/Report/Conference proceedingChapter


Urogenital schistosomiasis remains a major global challenge. Optimal management of this infection depends upon imaging-based assessment of sequelae. Although established imaging modalities such as ultrasonography, plain radiography, magnetic resonance imaging (MRI), narrow band imaging, and computerized tomography (CT) have been used to determine tissue involvement by urogenital schistosomiasis, newer refinements in associated technologies may lead to improvements in patient care. Moreover, application of investigational imaging methods such as confocal laser endomicroscopy and two-photon microscopy in animal models of urogenital schistosomiasis are likely to contribute to our understanding of this infection's pathogenesis. This review discusses prior use of imaging in patients with urogenital schistosomiasis and experimentally infected animals, the advantages and limitations of these modalities, the latest radiologic developments relevant to this infection, and a proposed future diagnostic standard of care for management of afflicted patients.

Original languageEnglish (US)
Title of host publicationAdvances in Parasitology
EditorsDavid Rollinson, Russell Stothard
PublisherAcademic Press
Number of pages26
ISBN (Print)9780323900836
StatePublished - Jan 2021

Publication series

NameAdvances in Parasitology
ISSN (Print)0065-308X


  • Confocal laser endomicroscopy
  • Endoscopy
  • Fluorescence imaging
  • Imaging
  • Schistosomiasis
  • Two-photon microscopy
  • Ultrasound
  • Urogenital schistosomiasis

ASJC Scopus subject areas

  • Parasitology


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