Lymphovascular Genomics and Proteomics, Clinical Syndromes, and Cancer Metastasis

Robert P. Erickson; Michael T. Dellinger

doi:10.1007/978-3-030-93084-4_23

Lymphovascular Genomics and Proteomics, Clinical Syndromes, and Cancer Metastasis

Robert P. Erickson, Michael T. Dellinger

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

The number of genetic mutations that cause lymphedema and other diseases of the lymphatic system has significantly grown in recent years. This information has shed light on the molecular mechanisms controlling the development of the lymphatic system and has increased our understanding of the etiology of inherited and non-inherited diseases of the lymphatic system. Here, we briefly describe the different genetic mutations that cause diseases of the lymphatic system, some of which are also mutated in some cancers. Additionally, we discuss the similarities between lymphatic diseases and cancer.

Original language	English (US)
Title of host publication	Cancer Metastasis Through the Lymphovascular System
Publisher	Springer International Publishing
Pages	241-247
Number of pages	7
ISBN (Electronic)	9783030930844
ISBN (Print)	9783030930837
DOIs	https://doi.org/10.1007/978-3-030-93084-4_23
State	Published - Jan 1 2022

Keywords

Gorham
Kaposiform lymphangiomatosis
Lymphatic development
Lymphatic malformation
Lymphedema
Stout disease

ASJC Scopus subject areas

General Medicine
General Immunology and Microbiology

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10.1007/978-3-030-93084-4_23

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AU - Dellinger, Michael T.

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AB - The number of genetic mutations that cause lymphedema and other diseases of the lymphatic system has significantly grown in recent years. This information has shed light on the molecular mechanisms controlling the development of the lymphatic system and has increased our understanding of the etiology of inherited and non-inherited diseases of the lymphatic system. Here, we briefly describe the different genetic mutations that cause diseases of the lymphatic system, some of which are also mutated in some cancers. Additionally, we discuss the similarities between lymphatic diseases and cancer.

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KW - Lymphatic development

KW - Lymphatic malformation

KW - Lymphedema

KW - Stout disease

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Lymphovascular Genomics and Proteomics, Clinical Syndromes, and Cancer Metastasis

Abstract

Keywords

ASJC Scopus subject areas

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