TY - JOUR
T1 - Lower limb revascularization for PAD using a heparin-coated PTFE conduit
AU - Kirkwood, Melissa L.
AU - Wang, Grace J.
AU - Jackson, Benjamin M.
AU - Golden, Michael A.
AU - Fairman, Ronald M.
AU - Woo, Edward Y.
PY - 2011/5
Y1 - 2011/5
N2 - Objective: To assess the patency of the PROPATEN Graft in lower extremity bypasses. Methods: We retrospectively reviewed all lower extremity bypasses with the PROPATEN Graft from 2007-2009 at a single institution. There were 68 implants-56% male; mean age 69. Comorbidities included hypertension (HTN; 81%), hyperlipidemia (72%), coronary artery disease (CAD; 74%), and smoking (59%). Most patients were Rutherford category 4 or higher. A total of 34% of patients had only 1 runoff vessel; 10% of patients required a complex concomitant procedure with sequential extremity revascularization. Statistics were via Kaplan Meier. Results: Mean follow-up was10.4±8.0 months (0-30). Patency was excellent in all positions. Primary patency for all patients was 94.0% and 86.0% at 30 days and 18 months, respectively. Limb salvage at 30 days was 95%, and at 18 months was 90%. No patients developed HIT. Ten patients lost graft patency. These patients had severe Peripheral Vascular Disease (PVD), with rest pain or tissue loss, poor runoff (no runoff or single vessel runoff), compromised inflow, and restored competitive flow. Fifty percent of the failed grafts were in the infrapopliteal position. Endovascular intervention and graft thrombectomy to restore patency was attempted in 2 patients and was unsuccessful. Conclusion: The GORE PROPATEN Vascular Graft demonstrates excellent patency in all arterial positions and may be the conduit of choice for all prosthetic bypasses.
AB - Objective: To assess the patency of the PROPATEN Graft in lower extremity bypasses. Methods: We retrospectively reviewed all lower extremity bypasses with the PROPATEN Graft from 2007-2009 at a single institution. There were 68 implants-56% male; mean age 69. Comorbidities included hypertension (HTN; 81%), hyperlipidemia (72%), coronary artery disease (CAD; 74%), and smoking (59%). Most patients were Rutherford category 4 or higher. A total of 34% of patients had only 1 runoff vessel; 10% of patients required a complex concomitant procedure with sequential extremity revascularization. Statistics were via Kaplan Meier. Results: Mean follow-up was10.4±8.0 months (0-30). Patency was excellent in all positions. Primary patency for all patients was 94.0% and 86.0% at 30 days and 18 months, respectively. Limb salvage at 30 days was 95%, and at 18 months was 90%. No patients developed HIT. Ten patients lost graft patency. These patients had severe Peripheral Vascular Disease (PVD), with rest pain or tissue loss, poor runoff (no runoff or single vessel runoff), compromised inflow, and restored competitive flow. Fifty percent of the failed grafts were in the infrapopliteal position. Endovascular intervention and graft thrombectomy to restore patency was attempted in 2 patients and was unsuccessful. Conclusion: The GORE PROPATEN Vascular Graft demonstrates excellent patency in all arterial positions and may be the conduit of choice for all prosthetic bypasses.
KW - Heparin bonded ePTFE
KW - Lower extremity bypass
KW - PROPATEN
UR - http://www.scopus.com/inward/record.url?scp=80052770029&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=80052770029&partnerID=8YFLogxK
U2 - 10.1177/1538574411401757
DO - 10.1177/1538574411401757
M3 - Article
C2 - 21444347
AN - SCOPUS:80052770029
SN - 1538-5744
VL - 45
SP - 329
EP - 334
JO - Vascular and Endovascular Surgery
JF - Vascular and Endovascular Surgery
IS - 4
ER -