Living donor liver paired exchange: A North American first

Madhukar S. Patel; Zubaida Mohamed; Anand Ghanekar; Gonzalo Sapisochin; Ian McGilvray; Blayne A. Sayed; Trevor Reichman; Markus Selzner; Jed A. Gross; Zita Galvin; Mamatha Bhat; Les Lilly; Mark Cattral; Nazia Selzner

doi:10.1111/ajt.16137

Living donor liver paired exchange: A North American first

Madhukar S. Patel, Zubaida Mohamed, Anand Ghanekar, Gonzalo Sapisochin, Ian McGilvray, Blayne A. Sayed, Trevor Reichman, Markus Selzner, Jed A. Gross, Zita Galvin, Mamatha Bhat, Les Lilly, Mark Cattral, Nazia Selzner

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

Paired organ exchange can be used to circumvent living donor-recipient ABO incompatibilities. Herein, we present the first case of successful liver paired exchange in North America. This 2-way swap required 4 simultaneous operations: 2 living donor hepatectomies and 2 living donor liver transplants. A nondirected anonymous living donor gift initiated this domino exchange, alleviating an ABO incompatibility in the other donor-recipient pair. With careful attention to ethical and logistical issues, paired liver exchange is a feasible option to expand the donor pool for incompatible living liver donor-recipient pairs.

Original language	English (US)
Pages (from-to)	400-404
Number of pages	5
Journal	American Journal of Transplantation
Volume	21
Issue number	1
DOIs	https://doi.org/10.1111/ajt.16137
State	Published - Jan 2021
Externally published	Yes

Keywords

ABO incompatibility
clinical research/practice
donors and donation: living
donors and donation: paired exchange
liver transplantation/hepatology
liver transplantation: living donor

ASJC Scopus subject areas

Immunology and Allergy
Transplantation
Pharmacology (medical)

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10.1111/ajt.16137

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title = "Living donor liver paired exchange: A North American first",

abstract = "Paired organ exchange can be used to circumvent living donor-recipient ABO incompatibilities. Herein, we present the first case of successful liver paired exchange in North America. This 2-way swap required 4 simultaneous operations: 2 living donor hepatectomies and 2 living donor liver transplants. A nondirected anonymous living donor gift initiated this domino exchange, alleviating an ABO incompatibility in the other donor-recipient pair. With careful attention to ethical and logistical issues, paired liver exchange is a feasible option to expand the donor pool for incompatible living liver donor-recipient pairs.",

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AU - Mohamed, Zubaida

AU - Ghanekar, Anand

AU - Sapisochin, Gonzalo

AU - McGilvray, Ian

AU - Sayed, Blayne A.

AU - Reichman, Trevor

AU - Selzner, Markus

AU - Gross, Jed A.

AU - Galvin, Zita

AU - Bhat, Mamatha

AU - Lilly, Les

AU - Cattral, Mark

AU - Selzner, Nazia

PY - 2021/1

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AB - Paired organ exchange can be used to circumvent living donor-recipient ABO incompatibilities. Herein, we present the first case of successful liver paired exchange in North America. This 2-way swap required 4 simultaneous operations: 2 living donor hepatectomies and 2 living donor liver transplants. A nondirected anonymous living donor gift initiated this domino exchange, alleviating an ABO incompatibility in the other donor-recipient pair. With careful attention to ethical and logistical issues, paired liver exchange is a feasible option to expand the donor pool for incompatible living liver donor-recipient pairs.

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KW - donors and donation: paired exchange

KW - liver transplantation/hepatology

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Living donor liver paired exchange: A North American first

Abstract

Keywords

ASJC Scopus subject areas

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