Lipid modification of the 17-kilodalton membrane immunogen of Treponema pallidum determines macrophage activation as well as amphiphilicity

Medicine & Life Sciences

• Treponema pallidum 91%
• Macrophage Activation 77%
• Lipoproteins 47%
• Lipids 44%
• Membranes 40%
• Cysteine 31%
• Amino Acid Sequence 31%
• Nonidet P-40 24%
• Mercaptoethanol 22%
• Genomic Library 21%
• Palmitates 20%
• Protein Sorting Signals 18%
• Glutathione Transferase 17%
• Disulfides 17%
• Immunoblotting 16%
• Immunoprecipitation 16%
• Open Reading Frames 16%
• Sequence Analysis 15%
• Fatty Acids 14%
• Clone Cells 13%
• Proteins 12%
• Monoclonal Antibodies 12%
• Tumor Necrosis Factor-alpha 11%
• Escherichia coli 11%
• Amino Acids 11%
• Macrophages 11%
• Peptides 10%
• Genes 6%

Agriculture & Biology

• macrophage activation 100%
• Treponema pallidum 99%
• antigens 50%
• lipids 36%
• lipoproteins 28%
• cysteine 16%
• amino acid sequences 13%
• palmitates 11%
• mice 11%
• beta-mercaptoethanol 11%
• genomic libraries 10%
• tumor necrosis factor-alpha 10%
• structural genes 10%
• immunoblotting 9%
• disulfides 9%
• glutathione transferase 9%
• signal peptide 9%
• macrophages 8%
• monoclonal antibodies 8%
• open reading frames 7%
• polypeptides 7%
• sequence analysis 7%
• fatty acids 6%
• clones 6%
• proteins 6%
• Escherichia coli 6%
• molecular weight 5%
• amino acids 5%
• cells 3%