Latest developments in chronic total occlusion percutaneous coronary intervention

Ilias Nikolakopoulos, Evangelia Vemmou, Judit Karacsonyi, Iosif Xenogiannis, Gerald S. Werner, Anthony H. Gershlick, Stephane Rinfret, Masahisa Yamane, Alexandre Avran, Mohaned Egred, Santiago Garcia, M. Nicholas Burke, Emmanouil S. Brilakis

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations


Introduction: Chronic Total Occlusion Percutaneous Coronary Intervention (CTO PCI) is now performed with high success rates and acceptable complication rates. Areas covered: We describe recent clinical and technological developments in CTO PCI from 2018 to 2020. Expert opinion: After publication of six randomized controlled trials, improving patient symptoms remains the principal indication for CTO PCI. Although good outcomes can be achieved with CTO PCI at experienced centers, success rates are significantly lower at less experienced centers, despite increased use in CTO crossing algorithms and development of novel and improved equipment and techniques.

Original languageEnglish (US)
Pages (from-to)415-426
Number of pages12
JournalExpert Review of Cardiovascular Therapy
StatePublished - 2020
Externally publishedYes


  • Chronic total occlusion
  • coronary artery disease
  • coronary occlusion percutaneous coronary intervention
  • stent

ASJC Scopus subject areas

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine


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