Krebs takes a turn at cell differentiation

Stanisław Deja, Peter A. Crawford, Shawn C Burgess

Research output: Contribution to journalComment/debatepeer-review

1 Scopus citations


In a recent issue of Nature, Arnold et al. report that the partitioning of citrate away from the oxidative steps of the tricarboxylic acid cycle and into the citrate-malate shuttle is essential for mouse embryonic stem cell differentiation. Their findings highlight a crucial role for metabolic regulation in developmental biology.

Original languageEnglish (US)
Pages (from-to)658-660
Number of pages3
JournalCell Metabolism
Issue number5
StatePublished - May 3 2022

ASJC Scopus subject areas

  • Physiology
  • Molecular Biology
  • Cell Biology


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