Kindr Motors Drive in Meiosis

Courtney M. Schroeder; Harmit S. Malik

doi:10.1016/j.cell.2018.04.021

Kindr Motors Drive in Meiosis

Courtney M. Schroeder, Harmit S. Malik

Research output: Contribution to journal › Short survey › peer-review

4 Scopus citations

Abstract

The discovery of neocentromere activity by maize knobs heralded the field of meiotic drive, in which selfish genetic elements exploit meiotic asymmetry to enhance their propagation. A new study reveals the long-awaited basis of this meiotic drive: cytoskeletal motors enable neocentromeric knobs to achieve favorable meiotic positioning and preferential inheritance. The discovery of neocentromere activity by maize knobs heralded the field of meiotic drive, in which selfish genetic elements exploit meiotic asymmetry to enhance their propagation. A new study reveals the long-awaited basis of this meiotic drive: cytoskeletal motors enable neocentromeric knobs to achieve favorable meiotic positioning and preferential inheritance.

Original language	English (US)
Pages (from-to)	813-815
Number of pages	3
Journal	Cell
Volume	173
Issue number	4
DOIs	https://doi.org/10.1016/j.cell.2018.04.021
State	Published - May 3 2018
Externally published	Yes

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

Access to Document

10.1016/j.cell.2018.04.021

Cite this

@article{195c36cc4abe43dda4285d6ee67d13aa,

title = "Kindr Motors Drive in Meiosis",

abstract = "The discovery of neocentromere activity by maize knobs heralded the field of meiotic drive, in which selfish genetic elements exploit meiotic asymmetry to enhance their propagation. A new study reveals the long-awaited basis of this meiotic drive: cytoskeletal motors enable neocentromeric knobs to achieve favorable meiotic positioning and preferential inheritance. The discovery of neocentromere activity by maize knobs heralded the field of meiotic drive, in which selfish genetic elements exploit meiotic asymmetry to enhance their propagation. A new study reveals the long-awaited basis of this meiotic drive: cytoskeletal motors enable neocentromeric knobs to achieve favorable meiotic positioning and preferential inheritance.",

author = "Schroeder, {Courtney M.} and Malik, {Harmit S.}",

note = "Funding Information: We are supported by a Jane Coffin Childs postdoctoral fellowship (C.M.S.), and R01GM074108 and HHMI (H.S.M.). We thank Rini Kasinathan, Michelle Hays, and Antoine Molaro for comments and R. Kelly Dawe for the maize cob images used in Figure 1B. Funding Information: We are supported by a Jane Coffin Childs postdoctoral fellowship (C.M.S.), and R01GM074108 and HHMI (H.S.M.). We thank Rini Kasinathan, Michelle Hays, and Antoine Molaro for comments and R. Kelly Dawe for the maize cob images used in Figure 1 B. Publisher Copyright: {\textcopyright} 2018 Elsevier Inc.",

year = "2018",

month = may,

day = "3",

doi = "10.1016/j.cell.2018.04.021",

language = "English (US)",

volume = "173",

pages = "813--815",

journal = "Cell",

issn = "0092-8674",

publisher = "Cell Press",

number = "4",

}

TY - JOUR

T1 - Kindr Motors Drive in Meiosis

AU - Schroeder, Courtney M.

AU - Malik, Harmit S.

N1 - Funding Information: We are supported by a Jane Coffin Childs postdoctoral fellowship (C.M.S.), and R01GM074108 and HHMI (H.S.M.). We thank Rini Kasinathan, Michelle Hays, and Antoine Molaro for comments and R. Kelly Dawe for the maize cob images used in Figure 1B. Funding Information: We are supported by a Jane Coffin Childs postdoctoral fellowship (C.M.S.), and R01GM074108 and HHMI (H.S.M.). We thank Rini Kasinathan, Michelle Hays, and Antoine Molaro for comments and R. Kelly Dawe for the maize cob images used in Figure 1 B. Publisher Copyright: © 2018 Elsevier Inc.

PY - 2018/5/3

Y1 - 2018/5/3

N2 - The discovery of neocentromere activity by maize knobs heralded the field of meiotic drive, in which selfish genetic elements exploit meiotic asymmetry to enhance their propagation. A new study reveals the long-awaited basis of this meiotic drive: cytoskeletal motors enable neocentromeric knobs to achieve favorable meiotic positioning and preferential inheritance. The discovery of neocentromere activity by maize knobs heralded the field of meiotic drive, in which selfish genetic elements exploit meiotic asymmetry to enhance their propagation. A new study reveals the long-awaited basis of this meiotic drive: cytoskeletal motors enable neocentromeric knobs to achieve favorable meiotic positioning and preferential inheritance.

AB - The discovery of neocentromere activity by maize knobs heralded the field of meiotic drive, in which selfish genetic elements exploit meiotic asymmetry to enhance their propagation. A new study reveals the long-awaited basis of this meiotic drive: cytoskeletal motors enable neocentromeric knobs to achieve favorable meiotic positioning and preferential inheritance. The discovery of neocentromere activity by maize knobs heralded the field of meiotic drive, in which selfish genetic elements exploit meiotic asymmetry to enhance their propagation. A new study reveals the long-awaited basis of this meiotic drive: cytoskeletal motors enable neocentromeric knobs to achieve favorable meiotic positioning and preferential inheritance.

UR - http://www.scopus.com/inward/record.url?scp=85046170806&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85046170806&partnerID=8YFLogxK

U2 - 10.1016/j.cell.2018.04.021

DO - 10.1016/j.cell.2018.04.021

M3 - Short survey

C2 - 29727667

AN - SCOPUS:85046170806

SN - 0092-8674

VL - 173

SP - 813

EP - 815

JO - Cell

JF - Cell

IS - 4

ER -

Kindr Motors Drive in Meiosis

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this