Abstract
Components of the immune system can impact diseases of the central nervous system (CNS). This chapter is designed to introduce the reader to immunological discoveries that changed the research community's perspective on many diseases of the CNS. Many of these discoveries were made using samples of cerebrospinal fluid, which is a part of the human CNS that we can readily access. Thus, this chapter focuses on research findings of the CSF that have advanced our understanding of certain CNS diseases. This chapter also provides primary literature for these discoveries, and several recent review articles that will provide a useful foundation for subsequent chapters in this book.
| Original language | English (US) |
|---|---|
| Title of host publication | Neuroimmunology |
| Subtitle of host publication | Multiple Sclerosis, Autoimmune Neurology and Related Diseases |
| Publisher | Springer International Publishing |
| Pages | 3-13 |
| Number of pages | 11 |
| ISBN (Electronic) | 9783030618834 |
| ISBN (Print) | 9783030618827 |
| DOIs | |
| State | Published - Apr 9 2021 |
Keywords
- B cells
- Blood-brain barrier
- Central nervous system
- Cerebrospinal fluid
- Cytokines
- Human
- Immunology
- Inflammation
- Innate cells
- T cells
ASJC Scopus subject areas
- General Medicine
- General Immunology and Microbiology