TY - JOUR
T1 - Intraventricular hemorrhage from ruptured aneurysm
T2 - Clinical characteristics, complications, and outcomes in a large, prospective, multicenter study population
AU - Rosen, David S.
AU - Macdonald, R. Loch
AU - Huo, Dezheng
AU - Goldenberg, Fernando D.
AU - Novakovic, Roberta L.
AU - Frank, Jeffrey I.
AU - Rosengart, Axel J.
PY - 2007/8
Y1 - 2007/8
N2 - Object. In this study the authors analyzed the relationship of intraventricular hemorrhage (IVH) to in-hospital complications and clinical outcome in a large population of patients with aneurysmal subarachnoid hemorrhage (SAH). Methods. Data from 3539 patients with aneurysmal SAH were evaluated, and these data were obtained from four prospective, randomized, double-blind, placebo-controlled trials of tirilazad that had been conducted between 1991 and 1997. Clinical characteristics, in-hospital complications, and outcome at 3 months post-SAH (Glasgow Outcome Scale score) were analyzed with regard to the presence or absence of IVH. Results. Patients with SAH and IVH differ in demographic and admission characteristics from those with SAH but without IVH and are more likely to suffer in-hospital complications and a worse outcome at 3 months post-SAH. Conclusions. The presence of IVH in patients with SAH has an important predictive value with regard to these aspects.
AB - Object. In this study the authors analyzed the relationship of intraventricular hemorrhage (IVH) to in-hospital complications and clinical outcome in a large population of patients with aneurysmal subarachnoid hemorrhage (SAH). Methods. Data from 3539 patients with aneurysmal SAH were evaluated, and these data were obtained from four prospective, randomized, double-blind, placebo-controlled trials of tirilazad that had been conducted between 1991 and 1997. Clinical characteristics, in-hospital complications, and outcome at 3 months post-SAH (Glasgow Outcome Scale score) were analyzed with regard to the presence or absence of IVH. Results. Patients with SAH and IVH differ in demographic and admission characteristics from those with SAH but without IVH and are more likely to suffer in-hospital complications and a worse outcome at 3 months post-SAH. Conclusions. The presence of IVH in patients with SAH has an important predictive value with regard to these aspects.
KW - Cerebral infarction
KW - Intraventricular hemorrhage
KW - Outcome
KW - Subarachnoid hemorrhage vasospasm
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U2 - 10.3171/JNS-07/08/0261
DO - 10.3171/JNS-07/08/0261
M3 - Article
C2 - 17695378
AN - SCOPUS:34547669172
SN - 0022-3085
VL - 107
SP - 261
EP - 265
JO - Journal of neurosurgery
JF - Journal of neurosurgery
IS - 2
ER -