TY - JOUR
T1 - Insulin Resistance - A Secret Killer?
AU - Foster, D. W.
PY - 1989/3/16
Y1 - 1989/3/16
N2 - In his Banting Lecture in 1988, Reaven coined the term “Syndrome X” to describe the following constellation: resistance to insulin-stimulated glucose uptake, glucose intolerance, hyperinsulinemia, increased levels of very-low-density lipoprotein (VLDL) triglyceride, decreased levels of high-density lipoprotein (HDL) cholesterol, and hypertension.1 The phenomenon of insulin resistance is well known in obesity, polycystic ovary syndrome, diabetes mellitus, lupus and other autoimmune diseases characterized by antibodies to the insulin receptor, partial or complete lipodystrophy, rare disorders such as leprechaunism, and a variety of endocrine diseases.2 It is generally considered to be secondary in these conditions, with a reversion to normal if the.
AB - In his Banting Lecture in 1988, Reaven coined the term “Syndrome X” to describe the following constellation: resistance to insulin-stimulated glucose uptake, glucose intolerance, hyperinsulinemia, increased levels of very-low-density lipoprotein (VLDL) triglyceride, decreased levels of high-density lipoprotein (HDL) cholesterol, and hypertension.1 The phenomenon of insulin resistance is well known in obesity, polycystic ovary syndrome, diabetes mellitus, lupus and other autoimmune diseases characterized by antibodies to the insulin receptor, partial or complete lipodystrophy, rare disorders such as leprechaunism, and a variety of endocrine diseases.2 It is generally considered to be secondary in these conditions, with a reversion to normal if the.
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U2 - 10.1056/NEJM198903163201111
DO - 10.1056/NEJM198903163201111
M3 - Editorial
C2 - 2646538
AN - SCOPUS:0024972129
SN - 0028-4793
VL - 320
SP - 733
EP - 734
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 11
ER -