TY - JOUR
T1 - Inherited and Acquired Choreas
AU - de Gusmao, Claudio M.
AU - Waugh, Jeff L.
N1 - Publisher Copyright:
© 2018 Elsevier Inc.
PY - 2018/4
Y1 - 2018/4
N2 - Chorea is a symptom of a broad array of genetic, structural, and metabolic disorders. While chorea can result from systemic illness and damage to diverse brain structures, injury to the basal ganglia, especially the putamen or globus pallidus, appears to be a uniting features of these diverse neuropathologies. The timing of onset, rate of progression, and the associated neurological or systemic symptoms can often narrow the differential diagnosis to a few disorders. Recognizing the correct etiology for childhood chorea is critical, as numerous disorders in this category are potentially curable, or are remediable, with early treatment.
AB - Chorea is a symptom of a broad array of genetic, structural, and metabolic disorders. While chorea can result from systemic illness and damage to diverse brain structures, injury to the basal ganglia, especially the putamen or globus pallidus, appears to be a uniting features of these diverse neuropathologies. The timing of onset, rate of progression, and the associated neurological or systemic symptoms can often narrow the differential diagnosis to a few disorders. Recognizing the correct etiology for childhood chorea is critical, as numerous disorders in this category are potentially curable, or are remediable, with early treatment.
UR - http://www.scopus.com/inward/record.url?scp=85042371495&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85042371495&partnerID=8YFLogxK
U2 - 10.1016/j.spen.2018.01.002
DO - 10.1016/j.spen.2018.01.002
M3 - Article
C2 - 29735116
AN - SCOPUS:85042371495
SN - 1071-9091
VL - 25
SP - 42
EP - 53
JO - Seminars in Pediatric Neurology
JF - Seminars in Pediatric Neurology
ER -