Influence of Long Term Fat-Feeding on Excretion of Cholesterol-4-C14 Metabolites

Jean D. Wilson; Marvin D. Siperstein

doi:10.3181/00379727-99-24265

Influence of Long Term Fat-Feeding on Excretion of Cholesterol-4-C¹⁴ Metabolites

Jean D. Wilson, Marvin D. Siperstein

Internal Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Effects of long-term feeding of various types and amounts of fat on fecal cholesterol excretion are reported. Diets containing 30% corn oil produce marked acceleration in excretion of C¹⁴ as non-digitonin precipitable neutral sterols in rat feces, accounting in these animals for 17–25% of the administered C¹⁴. This non-digitonin precipitable neutral sterol does not contain a ketonic group and is presumably a 3-alphahydroxy sterol.

Original language	English (US)
Pages (from-to)	113-116
Number of pages	4
Journal	Proceedings of the Society for Experimental Biology and Medicine
Volume	99
Issue number	1
DOIs	https://doi.org/10.3181/00379727-99-24265
State	Published - Oct 1958

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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title = "Influence of Long Term Fat-Feeding on Excretion of Cholesterol-4-C14 Metabolites",

abstract = "Effects of long-term feeding of various types and amounts of fat on fecal cholesterol excretion are reported. Diets containing 30% corn oil produce marked acceleration in excretion of C14 as non-digitonin precipitable neutral sterols in rat feces, accounting in these animals for 17–25% of the administered C14. This non-digitonin precipitable neutral sterol does not contain a ketonic group and is presumably a 3-alphahydroxy sterol.",

author = "Wilson, {Jean D.} and Siperstein, {Marvin D.}",

note = "Funding Information: This work was supported by grants from the American Heart Assn., the Dallas Heart Assn., and by Research Grant of Nat. Heart Inst., U.S.P.H.S.",

year = "1958",

month = oct,

doi = "10.3181/00379727-99-24265",

language = "English (US)",

volume = "99",

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journal = "Proceedings of the Society for Experimental Biology and Medicine",

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T1 - Influence of Long Term Fat-Feeding on Excretion of Cholesterol-4-C14 Metabolites

AU - Wilson, Jean D.

AU - Siperstein, Marvin D.

N1 - Funding Information: This work was supported by grants from the American Heart Assn., the Dallas Heart Assn., and by Research Grant of Nat. Heart Inst., U.S.P.H.S.

PY - 1958/10

Y1 - 1958/10

N2 - Effects of long-term feeding of various types and amounts of fat on fecal cholesterol excretion are reported. Diets containing 30% corn oil produce marked acceleration in excretion of C14 as non-digitonin precipitable neutral sterols in rat feces, accounting in these animals for 17–25% of the administered C14. This non-digitonin precipitable neutral sterol does not contain a ketonic group and is presumably a 3-alphahydroxy sterol.

AB - Effects of long-term feeding of various types and amounts of fat on fecal cholesterol excretion are reported. Diets containing 30% corn oil produce marked acceleration in excretion of C14 as non-digitonin precipitable neutral sterols in rat feces, accounting in these animals for 17–25% of the administered C14. This non-digitonin precipitable neutral sterol does not contain a ketonic group and is presumably a 3-alphahydroxy sterol.

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JO - Proceedings of the Society for Experimental Biology and Medicine

JF - Proceedings of the Society for Experimental Biology and Medicine

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Influence of Long Term Fat-Feeding on Excretion of Cholesterol-4-C¹⁴ Metabolites

Abstract

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