In vitro effects of iodinated arthrographic contrast media on bacterial growth

G. Leland Melson, R. C. McDaniel, P. M. Southern, T. W. Staple

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Several bacterial species causing septic arthritis and infection of prosthetic joints (Staphylococcus aureus, coagulase positive; Staphylococcus albus, coagulase negative; Streptococcus pyogenes, group A; Pseudomonas aeruginosa; Diplococcus pneumoniae; Neisseria gonorrhoeae; and Hemophilus influenzae, type b) were exposed in vitro to 3 common arthrographic contrast materials for 30 min. Quantitative cultures showed no significant inhibition of bacterial growth, compared to controls. All strains except D. pneumoniae and N. gonorrhoeae grew after contact with contrast media for up to 72 hr. Thus, arthrography with the tested contrast agents is not expected to interfere with the culturing of bacteria from subsequently aspirated specimens.

Original languageEnglish (US)
Pages (from-to)593-595
Number of pages3
Issue number3
StatePublished - Jan 1 1974

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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