Impact of physiological, pathological and environmental factors on the expression and activity of human cytochrome P450 2D6 and implications in precision medicine

Medicine & Life Sciences

• Cytochrome P-450 CYP2D6 100%
• Precision Medicine 85%
• Human Activities 79%
• Hepatocyte Nuclear Factor 4 17%
• Pharmaceutical Preparations 10%
• GW 4064 9%
• Epigenomics 9%
• Histone Code 6%
• Validation Studies 5%
• Phenobarbital 5%
• Rifampin 5%
• Genome-Wide Association Study 5%
• Liver 5%
• Post Translational Protein Processing 5%
• Cytoplasmic and Nuclear Receptors 5%
• Drug Interactions 5%
• Dexamethasone 4%
• Transcriptional Activation 4%
• Liver Diseases 4%
• Psychological Inhibition 4%
• Alcohols 3%
• Smoking 3%
• Genotype 3%
• Phosphorylation 3%
• Pregnancy 3%
• DNA 2%
• Enzymes 2%
• Kidney 2%
• Genes 2%