Immature platelet fraction as a biomarker for disease severity in pediatric respiratory coronavirus disease 2019

Nicholas C.J. Lee; Yusuf Kemal Demir; Bilal Ashraf; Ibrahim Ibrahim; Taha Bat; Kathryn E. Dickerson

doi:10.1016/j.jpeds.2022.07.035

Immature platelet fraction as a biomarker for disease severity in pediatric respiratory coronavirus disease 2019

Nicholas C.J. Lee, Yusuf Kemal Demir, Bilal Ashraf, Ibrahim Ibrahim, Taha Bat, Kathryn E. Dickerson

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

In this retrospective single-institution cohort study of 113 hospitalized pediatric patients with respiratory coronavirus disease 2019, those admitted to the intensive care unit or requiring mechanical ventilation had significantly higher immature platelet fractions than those who did not require intensive care unit–level care or ventilation. Immature platelet fraction may be an accessible biomarker for disease severity in pediatric respiratory coronavirus disease 2019.

Original language	English (US)
Journal	Journal of Pediatrics
DOIs	https://doi.org/10.1016/j.jpeds.2022.07.035
State	Accepted/In press - 2022

Keywords

biomarker
COVID-19
immature platelet
pediatric
SARS-CoV-2

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

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10.1016/j.jpeds.2022.07.035

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title = "Immature platelet fraction as a biomarker for disease severity in pediatric respiratory coronavirus disease 2019",

abstract = "In this retrospective single-institution cohort study of 113 hospitalized pediatric patients with respiratory coronavirus disease 2019, those admitted to the intensive care unit or requiring mechanical ventilation had significantly higher immature platelet fractions than those who did not require intensive care unit–level care or ventilation. Immature platelet fraction may be an accessible biomarker for disease severity in pediatric respiratory coronavirus disease 2019.",

keywords = "biomarker, COVID-19, immature platelet, pediatric, SARS-CoV-2",

author = "Lee, {Nicholas C.J.} and Demir, {Yusuf Kemal} and Bilal Ashraf and Ibrahim Ibrahim and Taha Bat and Dickerson, {Kathryn E.}",

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language = "English (US)",

journal = "Journal of Pediatrics",

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AU - Lee, Nicholas C.J.

AU - Demir, Yusuf Kemal

AU - Ashraf, Bilal

AU - Ibrahim, Ibrahim

AU - Bat, Taha

AU - Dickerson, Kathryn E.

PY - 2022

Y1 - 2022

N2 - In this retrospective single-institution cohort study of 113 hospitalized pediatric patients with respiratory coronavirus disease 2019, those admitted to the intensive care unit or requiring mechanical ventilation had significantly higher immature platelet fractions than those who did not require intensive care unit–level care or ventilation. Immature platelet fraction may be an accessible biomarker for disease severity in pediatric respiratory coronavirus disease 2019.

AB - In this retrospective single-institution cohort study of 113 hospitalized pediatric patients with respiratory coronavirus disease 2019, those admitted to the intensive care unit or requiring mechanical ventilation had significantly higher immature platelet fractions than those who did not require intensive care unit–level care or ventilation. Immature platelet fraction may be an accessible biomarker for disease severity in pediatric respiratory coronavirus disease 2019.

KW - biomarker

KW - COVID-19

KW - immature platelet

KW - pediatric

KW - SARS-CoV-2

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DO - 10.1016/j.jpeds.2022.07.035

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SN - 0022-3476

JO - Journal of Pediatrics

JF - Journal of Pediatrics

ER -

Immature platelet fraction as a biomarker for disease severity in pediatric respiratory coronavirus disease 2019

Abstract

Keywords

ASJC Scopus subject areas

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