Imipramine and social-vocational adjustment in chronic depression

J. H. Kocsis, A. J. Frances, C. Voss, B. J. Mason, J. J. Mann, J. Sweeney

Research output: Contribution to journalArticlepeer-review

74 Scopus citations


The authors compared the effects of 6 weeks of imipramine treatment with 6 weeks of placebo treatment on social and vocational impairment in chronic depression. Imipramine was associated with significantly greater pre- to posttreatment improvement of social-vocational impairments in chronic depression, suggesting that these impairments may have represented affective symptoms rather than characterologic deficits.

Original languageEnglish (US)
Pages (from-to)997-999
Number of pages3
JournalAmerican Journal of Psychiatry
Issue number8
StatePublished - 1988

ASJC Scopus subject areas

  • Psychiatry and Mental health


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