TY - JOUR
T1 - Imaging and Interventions for Lymphatic and Lymphatic-related Disorders
AU - Benjamin, Jamaal
AU - O'Leary, Cathal
AU - Hur, Saebeom
AU - Gurevich, Alexey
AU - Klein, Willemijn M.
AU - Itkin, Maxim
N1 - Publisher Copyright:
© RSNA, 2023.
PY - 2023/5
Y1 - 2023/5
N2 - The lymphatic system is critical in fluid balance homeostasis. Yet, until recently, lymphatic imaging has been outside of mainstream medicine due to a lack of robust imaging and interventional options. However, during the last 20 years, both clinical lymphatic imaging and interventions have shown dramatic advancement. The key to imaging advancement has been the interstitial delivery of contrast agents through lymphatic-rich tissues. These techniques include intranodal lymphangiography and dynamic contrast-enhanced MR lymphangiography. These methods provide the ability to image and recognize lymphatic anatomy and pathologic conditions. Percutaneous thoracic duct catheterization and embolization became the first widely accepted interventional technique for the management of chyle leaks. Advances in interstitial lymphatic embolization, as well as liver and mesenteric lymphatic interventions, have broadened the scope of possible lymphatic interventions. Also, recent techniques of lymphatic decompression allow for the treatment of a variety of lymphatic disorders. Finally, immunologic studies of central lymphatic fluid reveal the potential of lymphatic interventions on immunity. These advances herald an exciting new chapter for lymphatic imaging and interventions in the coming years.
AB - The lymphatic system is critical in fluid balance homeostasis. Yet, until recently, lymphatic imaging has been outside of mainstream medicine due to a lack of robust imaging and interventional options. However, during the last 20 years, both clinical lymphatic imaging and interventions have shown dramatic advancement. The key to imaging advancement has been the interstitial delivery of contrast agents through lymphatic-rich tissues. These techniques include intranodal lymphangiography and dynamic contrast-enhanced MR lymphangiography. These methods provide the ability to image and recognize lymphatic anatomy and pathologic conditions. Percutaneous thoracic duct catheterization and embolization became the first widely accepted interventional technique for the management of chyle leaks. Advances in interstitial lymphatic embolization, as well as liver and mesenteric lymphatic interventions, have broadened the scope of possible lymphatic interventions. Also, recent techniques of lymphatic decompression allow for the treatment of a variety of lymphatic disorders. Finally, immunologic studies of central lymphatic fluid reveal the potential of lymphatic interventions on immunity. These advances herald an exciting new chapter for lymphatic imaging and interventions in the coming years.
UR - http://www.scopus.com/inward/record.url?scp=85153361465&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85153361465&partnerID=8YFLogxK
U2 - 10.1148/RADIOL.220231
DO - 10.1148/RADIOL.220231
M3 - Review article
C2 - 36943078
AN - SCOPUS:85153361465
SN - 0033-8419
VL - 307
JO - RADIOLOGY
JF - RADIOLOGY
IS - 3
M1 - e220321
ER -