Illuminating the role of vitamin a in skin innate immunity and the skin microbiome: A narrative review

Fritzlaine C. Roche; Tamia A. Harris-Tryon

doi:10.3390/nu13020302

Illuminating the role of vitamin a in skin innate immunity and the skin microbiome: A narrative review

Fritzlaine C. Roche, Tamia A. Harris-Tryon

Research output: Contribution to journal › Review article › peer-review

13 Scopus citations

Abstract

Vitamin A is a fat-soluble vitamin that plays an important role in skin immunity. Deficien-cies in Vitamin A have been linked to impaired immune response and increased susceptibility to skin infections and inflammatory skin disease. This narrative review summarizes recent primary evidence that elucidates the role of vitamin A and its derivatives on innate immune regulators through mechanisms that promote skin immunity and sustain the skin microbiome.

Original language	English (US)
Article number	302
Pages (from-to)	1-9
Number of pages	9
Journal	Nutrients
Volume	13
Issue number	2
DOIs	https://doi.org/10.3390/nu13020302
State	Published - Feb 2021

Keywords

Innate immunity
Retinoic acid
Skin immunity
Skin microbiome
Vitamin A

ASJC Scopus subject areas

Food Science
Nutrition and Dietetics

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10.3390/nu13020302

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title = "Illuminating the role of vitamin a in skin innate immunity and the skin microbiome: A narrative review",

abstract = "Vitamin A is a fat-soluble vitamin that plays an important role in skin immunity. Deficien-cies in Vitamin A have been linked to impaired immune response and increased susceptibility to skin infections and inflammatory skin disease. This narrative review summarizes recent primary evidence that elucidates the role of vitamin A and its derivatives on innate immune regulators through mechanisms that promote skin immunity and sustain the skin microbiome.",

keywords = "Innate immunity, Retinoic acid, Skin immunity, Skin microbiome, Vitamin A",

author = "Roche, {Fritzlaine C.} and Harris-Tryon, {Tamia A.}",

note = "Funding Information: Funding: This research was funded by Dermatology Foundation Diversity Supplement Award. Funding Information: Acknowledgments: We thank the Dermatology Foundation for their support of the research grant. Publisher Copyright: {\textcopyright} 2021 by the authors. Licensee MDPI, Basel, Switzerland.",

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AU - Harris-Tryon, Tamia A.

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N2 - Vitamin A is a fat-soluble vitamin that plays an important role in skin immunity. Deficien-cies in Vitamin A have been linked to impaired immune response and increased susceptibility to skin infections and inflammatory skin disease. This narrative review summarizes recent primary evidence that elucidates the role of vitamin A and its derivatives on innate immune regulators through mechanisms that promote skin immunity and sustain the skin microbiome.

AB - Vitamin A is a fat-soluble vitamin that plays an important role in skin immunity. Deficien-cies in Vitamin A have been linked to impaired immune response and increased susceptibility to skin infections and inflammatory skin disease. This narrative review summarizes recent primary evidence that elucidates the role of vitamin A and its derivatives on innate immune regulators through mechanisms that promote skin immunity and sustain the skin microbiome.

KW - Innate immunity

KW - Retinoic acid

KW - Skin immunity

KW - Skin microbiome

KW - Vitamin A

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Illuminating the role of vitamin a in skin innate immunity and the skin microbiome: A narrative review

Abstract

Keywords

ASJC Scopus subject areas

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