Idiopathic thrombocytopenic purpura: Beyond consensus

Desiree Medeiros, George R. Buchanan

Research output: Contribution to journalReview articlepeer-review

38 Scopus citations


Idiopathic thrombocytopenic purpura (ITP) is the most common acquired bleeding disorder encountered by pediatricians. Most children with ITP have minimal bleeding and complete platelet count recovery within weeks to months. Therapy for ITP has ranged from close observation without medical intervention to aggressive management with corticosteroids, intravenous immunoglobulin G, or anti-D immune globulin. The topic of ITP has incited great debate among practitioners, and this debate prompted the development of ITP practice guidelines by the British Paediatric Haematology Group in 1992 and by the American Society of Hematology in 1996. A better understanding of the clinical course of, risk for significant bleeding in, and optimal evaluation and therapy of childhood ITP will require carefully designed, multicenter, clinical trials.

Original languageEnglish (US)
Pages (from-to)4-9
Number of pages6
JournalCurrent opinion in pediatrics
Issue number1
StatePublished - Jan 27 2000

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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