Hyperlipidemia and diabetes

F. L. Dunn

Research output: Contribution to journalArticlepeer-review

32 Scopus citations


Hyperlipidemia is a relatively common problem in patients with poorly controlled diabetes mellitus. It has been estimated that the frequency of elevated plasma lipid levels in diabetic patients is between 20 and 90 per cent, depending on the degree of diabetic control and the type of diabetes. Diabetics as a group tend to have higher plasma lipid levels than nondiabetics, and this abnormality is exaggerated in patients with 'poor' diabetic control. There are several reasons for this association. First, insulin plays an important role in the regulation of intermediary lipid metabolism, and fluctuations in the degree of diabetic control thus produce variable effects on plasma lipoprotein metabolism. Secondly, many non-insulin-dependent (Type 2) diabetic patients are obese, and obesity may lead to the development of hyperlipidemia. Third, although diabetes and hyperlipidemia represent different genetic disorders, each of these disorders is common in the population, and the two disorders may co-exist by chance in the same individual.

Original languageEnglish (US)
Pages (from-to)1347-1360
Number of pages14
JournalMedical Clinics of North America
Issue number6
StatePublished - Jan 1 1982

ASJC Scopus subject areas

  • Medicine(all)


Dive into the research topics of 'Hyperlipidemia and diabetes'. Together they form a unique fingerprint.

Cite this