Objective Clinical outcomes for enucleation vary widely, depending on surgical technique, implant choice, and indications for enucleation. The goal of this study was to compare complications of enucleation using hydroxyapatite versus polyethylene orbital implants for 1 indication: uveal melanoma in adults. Design Retrospective chart review Participants Consecutive case series of patients who were enucleated for uveal melanoma by a single surgeon (J.W.H.) from 1999-2009. Methods A retrospective chart review was performed to record clinical and histopathologic features, surgical technique, orbital implant characteristics, and outcomes in a consecutive series of patients with uveal melanoma who were treated by enucleation by a single surgeon (J.W.H.) between 1999 and 2009. Results This study included 139 patients; 64 received hydroxyapatite implants, and 75 received polyethylene implants wrapped in donor sclera. Complications included blepharoptosis in 4 (2.9%), conjunctival cyst in 2 (1.4%), volume deficit in 2 (1.4%), implant exposure in 1 (0.7%), and conjunctival erosion in 1 (0.7%) patient. There were no significant differences in the clinicopathologic features or complications between the 2 groups. Conclusions Few complications were encountered using this enucleation technique, and there was no difference in complication rates between patients receiving hydroxyapatite and polyethylene implants.
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