Hospital course and short-term outcomes of term and late preterm neonates following exposure to prolonged rupture of membranes and/or chorioamnionitis

Gregory L. Jackson; Patricia Rawiki; Dorothy Sendelbach; M. Denise Manning; William D. Engle

doi:10.1097/INF.0b013e31822fb15d

Hospital course and short-term outcomes of term and late preterm neonates following exposure to prolonged rupture of membranes and/or chorioamnionitis

Gregory L. Jackson, Patricia Rawiki, Dorothy Sendelbach, M. Denise Manning, William D. Engle

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23 Scopus citations

Abstract

Our objective was to characterize the hospital course and short-term outcomes of neonates exposed to prolonged rupture of membranes (PROM), chorioamnionitis (CH), or both PROM and CH. Outcomes were positive blood culture and/or clinical signs of infection (+BC/CSI) prompting >4 days of antibiotics. Six neonates had a positive BC, 2 (0.6%) in the CH group and 4 (2.7%) in the PROM + CH group (P = 0.05); none of the neonates exposed to PROM alone had a +BC. These results support our current approach of withholding routine antibiotic therapy in neonates exposed to PROM alone.

Original language	English (US)
Pages (from-to)	89-90
Number of pages	2
Journal	Pediatric Infectious Disease Journal
Volume	31
Issue number	1
DOIs	https://doi.org/10.1097/INF.0b013e31822fb15d
State	Published - Jan 1 2012

Keywords

chorioamnionitis
early onset neonatal sepsis
group B streptococcus
neonate
prolonged rupture of membranes

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Microbiology (medical)
Infectious Diseases

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10.1097/INF.0b013e31822fb15d

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abstract = "Our objective was to characterize the hospital course and short-term outcomes of neonates exposed to prolonged rupture of membranes (PROM), chorioamnionitis (CH), or both PROM and CH. Outcomes were positive blood culture and/or clinical signs of infection (+BC/CSI) prompting >4 days of antibiotics. Six neonates had a positive BC, 2 (0.6%) in the CH group and 4 (2.7%) in the PROM + CH group (P = 0.05); none of the neonates exposed to PROM alone had a +BC. These results support our current approach of withholding routine antibiotic therapy in neonates exposed to PROM alone.",

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Hospital course and short-term outcomes of term and late preterm neonates following exposure to prolonged rupture of membranes and/or chorioamnionitis

Abstract

Keywords

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