Abstract
Non-small-cell lung cancers with activating mutations in the epidermal growth factor receptor develop resistance to tyrosine kinase inhibitors by recruiting the MET receptor kinase to activate HER3 and the PI3K-Akt cell survival pathway.
Original language | English (US) |
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Pages (from-to) | 675-677 |
Number of pages | 3 |
Journal | Nature medicine |
Volume | 13 |
Issue number | 6 |
DOIs | |
State | Published - Jun 2007 |
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)