Hepatic mTORC1 Opposes Impaired Insulin Action to Control Mitochondrial Metabolism in Obesity

Keyphrases

• Obesity 100%
• Mitochondrial Metabolism 100%
• Mammalian Target of Rapamycin (mTOR) 100%
• Impaired Insulin Secretion 100%
• Insulin Action 50%
• Insulin Receptor 50%
• Liver 33%
• TSC1 33%
• Ketogenesis 33%
• Pathophysiology 16%
• Oxidative Stress 16%
• Catabolic 16%
• Hyperglycemia 16%
• Nutritional Status 16%
• Gluconeogenesis 16%
• Tricarboxylic Acid Cycle (TCA cycle) 16%
• Double Knockout 16%
• Anaplerosis 16%
• Dysregulated 16%
• Cycle Oxidation 16%
• Hepatic Insulin Resistance 16%
• Hepatic Mitochondria 16%
• Glucose Production 16%
• Glycogen Synthesis 16%
• Oxidative Inflammation 16%
• Glycogen Storage Disease 16%
• Elevated Glucose 16%

Biochemistry, Genetics and Molecular Biology

• Mitochondrial Respiration 100%
• Mammalian Target of Rapamycin Complex 1 100%
• Insulin Receptor 50%
• Gluconeogenesis 33%
• Ketogenesis 33%
• Mouse 16%
• Alpha Oxidation 16%
• Insulin Resistance 16%
• Hyperglycemia 16%
• Oxidative Stress 16%
• Citric Acid Cycle 16%
• Anaplerosis 16%
• Glycogenesis 16%