Hedgehog signaling pathway.

Leni Jacob; Lawrence Lum

doi:10.1126/stke.4072007cm6

Hedgehog signaling pathway.

Leni Jacob, Lawrence Lum

Research output: Contribution to journal › Review article › peer-review

19 Scopus citations

Abstract

The Hedgehog (Hh) signaling pathway is essential for development and tissue homeostasis in metazoans. Probably as a result of its potent influence on cell-fate outcomes, the Hh pathway when corrupted results in malformations and diseases such as cancer. Many of the pathway components that contribute to Hh-mediated signal transduction are presented.

Original language	English (US)
Pages (from-to)	cm6
Journal	Science's STKE : signal transduction knowledge environment
Volume	2007
Issue number	407
DOIs	https://doi.org/10.1126/stke.4072007cm6
State	Published - Oct 9 2007

ASJC Scopus subject areas

Medicine(all)

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10.1126/stke.4072007cm6

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title = "Hedgehog signaling pathway.",

abstract = "The Hedgehog (Hh) signaling pathway is essential for development and tissue homeostasis in metazoans. Probably as a result of its potent influence on cell-fate outcomes, the Hh pathway when corrupted results in malformations and diseases such as cancer. Many of the pathway components that contribute to Hh-mediated signal transduction are presented.",

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AU - Lum, Lawrence

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AB - The Hedgehog (Hh) signaling pathway is essential for development and tissue homeostasis in metazoans. Probably as a result of its potent influence on cell-fate outcomes, the Hh pathway when corrupted results in malformations and diseases such as cancer. Many of the pathway components that contribute to Hh-mediated signal transduction are presented.

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M3 - Review article

C2 - 17925577

AN - SCOPUS:35148849511

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SP - cm6

JO - Science's STKE : signal transduction knowledge environment

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ER -

Hedgehog signaling pathway.

Abstract

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