HDL action on the vascular wall: Is the answer NO?

Philip W. Shaul; Chieko Mineo

doi:10.1172/JCI200421072

HDL action on the vascular wall: Is the answer NO?

Philip W. Shaul, Chieko Mineo

Research output: Contribution to journal › Review article › peer-review

49 Scopus citations

Abstract

Circulating levels of HDL cholesterol are inversely related to the risk of atherosclerosis, and therapeutic increases in HDL reduce the incidence of cardiovascular events. A new study (see the related article beginning on page 569) shows that HDL-associated lysophospholipids stimulate the production of the potent antiatherogenic signaling molecule NO by the vascular endothelium.

Original language	English (US)
Pages (from-to)	509-513
Number of pages	5
Journal	Journal of Clinical Investigation
Volume	113
Issue number	4
DOIs	https://doi.org/10.1172/JCI200421072
State	Published - Feb 2004

ASJC Scopus subject areas

Medicine(all)

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10.1172/JCI200421072

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title = "HDL action on the vascular wall: Is the answer NO?",

abstract = "Circulating levels of HDL cholesterol are inversely related to the risk of atherosclerosis, and therapeutic increases in HDL reduce the incidence of cardiovascular events. A new study (see the related article beginning on page 569) shows that HDL-associated lysophospholipids stimulate the production of the potent antiatherogenic signaling molecule NO by the vascular endothelium.",

author = "Shaul, {Philip W.} and Chieko Mineo",

year = "2004",

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T2 - Is the answer NO?

AU - Shaul, Philip W.

AU - Mineo, Chieko

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N2 - Circulating levels of HDL cholesterol are inversely related to the risk of atherosclerosis, and therapeutic increases in HDL reduce the incidence of cardiovascular events. A new study (see the related article beginning on page 569) shows that HDL-associated lysophospholipids stimulate the production of the potent antiatherogenic signaling molecule NO by the vascular endothelium.

AB - Circulating levels of HDL cholesterol are inversely related to the risk of atherosclerosis, and therapeutic increases in HDL reduce the incidence of cardiovascular events. A new study (see the related article beginning on page 569) shows that HDL-associated lysophospholipids stimulate the production of the potent antiatherogenic signaling molecule NO by the vascular endothelium.

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U2 - 10.1172/JCI200421072

DO - 10.1172/JCI200421072

M3 - Review article

C2 - 14966559

AN - SCOPUS:1642416885

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VL - 113

SP - 509

EP - 513

JO - Journal of Clinical Investigation

JF - Journal of Clinical Investigation

IS - 4

ER -

HDL action on the vascular wall: Is the answer NO?

Abstract

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