Growth Competition in Interspecies Chimeras: A New Paradigm for Blastocyst Complementation

Emily B. Ballard; Jun Wu

doi:10.1016/j.stem.2020.12.011

Growth Competition in Interspecies Chimeras: A New Paradigm for Blastocyst Complementation

Emily B. Ballard, Jun Wu

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Blastocyst complementation represents a powerful technique for interspecies organogenesis but is limited by low chimerism due to developmental incompatibilities. In this issue of Cell Stem Cell, Nishimura et al. (2021) circumvent early developmental barriers by disabling Igf1r in host embryos, conferring donor cells with a growth advantage from mid-gestation onward.

Original language	English (US)
Pages (from-to)	3-5
Number of pages	3
Journal	Cell Stem Cell
Volume	28
Issue number	1
DOIs	https://doi.org/10.1016/j.stem.2020.12.011
State	Published - Jan 7 2021

ASJC Scopus subject areas

Molecular Medicine
Genetics
Cell Biology

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10.1016/j.stem.2020.12.011

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title = "Growth Competition in Interspecies Chimeras: A New Paradigm for Blastocyst Complementation",

abstract = "Blastocyst complementation represents a powerful technique for interspecies organogenesis but is limited by low chimerism due to developmental incompatibilities. In this issue of Cell Stem Cell, Nishimura et al. (2021) circumvent early developmental barriers by disabling Igf1r in host embryos, conferring donor cells with a growth advantage from mid-gestation onward.",

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Growth Competition in Interspecies Chimeras: A New Paradigm for Blastocyst Complementation

Abstract

ASJC Scopus subject areas

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