Granulomatous hepatitis associated with carbamazepine therapy

Mack C. Mitchell, John K. Boitnott, Alberto Arregui, Willis C. Maddrey

Research output: Contribution to journalArticlepeer-review

48 Scopus citations


Granulomatous hepatitis developed in two patients while they were receiving carbamazepine (Tegretol®). Both patients had evidence of hepatitis within one month of beginning the drug therapy and had a rapid and complete resolution once the agent was discontinued. In both, the liver biopsy contained granulomas in addition to acute portal inflammation. Carbamazepine should be added to the list of drugs causing granulomatous hepatitis.

Original languageEnglish (US)
Pages (from-to)733-735
Number of pages3
JournalThe American Journal of Medicine
Issue number4
StatePublished - Oct 1981

ASJC Scopus subject areas

  • Medicine(all)


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