GPU-based simulation of echocardiography volumes using quantitative fiber-angle-to-backscatter measurements

Megan Yociss, Baowei Fei

Research output: Chapter in Book/Report/Conference proceedingConference contribution


The intensity of backscattered ultrasound signal from heart muscle is known to be related to the angle between cardiac fibers and the insonification direction. In this work, a GPU-based method of simulating three-dimensional (3D) echocardiographic images from an empirically derived angle-to-backscatter relationship is developed and validated. Images of a rotating fiber phantom are simulated, and it is validated that the angle-to-backscatter relationship is accurately reflected by the simulated envelope data. In a second experiment, echocardiography images are simulated from a diffusion tensor magnetic resonance imaging (DT-MRI) volume of a canine heart to demonstrate that the method produces view-dependent speckle. 3D volumes of a parametrically generated ideal left ventricle phantom are also simulated and processed into fiber orientation maps using the underlying quantitative parameters. Images are simulated based on the characteristics of a 35-by-32 two-dimensional (2D) matrix array probe and a clinical one-dimensional (1D) phased array probe. The processed fiber volumes exhibit good agreement with the virtual phantom’s ground truth, having an average acute angle error (AAE) of less than 10 degrees for both probes. The simulation method is fast and opens a new approach for ultrasound fiber imaging.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2021
Subtitle of host publicationUltrasonic Imaging and Tomography
EditorsBrett C. Byram, Nicole V. Ruiter
ISBN (Electronic)9781510640337
StatePublished - 2021
EventMedical Imaging 2021: Ultrasonic Imaging and Tomography - Virtual, Online, United States
Duration: Feb 15 2021Feb 19 2021

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


ConferenceMedical Imaging 2021: Ultrasonic Imaging and Tomography
Country/TerritoryUnited States
CityVirtual, Online


  • Backscatter
  • Cardiac fiber orientation
  • Echocardiography
  • GPU
  • Matrix array
  • Myocardia
  • Quantification
  • Ultrasound probe
  • Ultrasound simulation
  • Volumetric ultrasound imaging

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging
  • Biomaterials


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