Gold-catalyzed 1,3-transposition of ynones

Roohollah Kazem Shiroodi; Mohammad Soltani; Vladimir Gevorgyan

doi:10.1021/ja504892c

Gold-catalyzed 1,3-transposition of ynones

Roohollah Kazem Shiroodi, Mohammad Soltani, Vladimir Gevorgyan

Research output: Contribution to journal › Article › peer-review

38 Scopus citations

Abstract

An efficient, regioselective gold-catalyzed 1,3-transposition reaction of ynones and diynones has been developed. It was found that stereoelectronic (interrupted conjugation) and electronic (extended conjugation) factors could efficiently govern the regioselectivity of this thermodynamically controlled transformation. The produced conjugated diynones were efficiently transformed into diverse alkyne-substituted five- and six-membered heterocycles.

Original language	English (US)
Pages (from-to)	9882-9885
Number of pages	4
Journal	Journal of the American Chemical Society
Volume	136
Issue number	28
DOIs	https://doi.org/10.1021/ja504892c
State	Published - Jul 16 2014
Externally published	Yes

ASJC Scopus subject areas

Catalysis
General Chemistry
Biochemistry
Colloid and Surface Chemistry

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AU - Gevorgyan, Vladimir

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Gold-catalyzed 1,3-transposition of ynones

Abstract

ASJC Scopus subject areas

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