Generation and characterization of an antagonistic monoclonal antibody against an extracellular domain of mouse DP2 (CRTH2/ GPR44) receptors for prostaglandin D2

Agriculture & Biology

• prostaglandins 55%
• monoclonal antibodies 53%
• receptors 40%
• mice 34%
• immunization 14%
• inflammation 13%
• inhibitory concentration 50 13%
• lymphocytes 12%
• arrestins 11%
• interleukin-3 10%
• antibodies 9%
• chemoattractants 9%
• G-protein coupled receptors 9%
• forskolin 8%
• sleep 8%
• in vivo studies 8%
• G-proteins 8%
• B-lymphocytes 7%
• cells 7%
• cytokines 7%
• animal models 6%
• Western blotting 6%
• enzyme-linked immunosorbent assay 6%
• staining 5%
• kidneys 5%
• mutants 4%
• lipids 4%
• proteins 2%

Medicine & Life Sciences

• prostaglandin D2 receptor 100%
• Monoclonal Antibodies 44%
• Inhibitory Concentration 50 13%
• CCR10 Receptors 13%
• Immunization 12%
• Arrestin 10%
• Formyl Peptide Receptor 10%
• Lymphocytes 10%
• Ureteral Obstruction 9%
• B-Lymphoid Precursor Cells 9%
• Th2 Cells 8%
• Interleukin-3 8%
• Inflammation 8%
• Antibodies 8%
• Colforsin 8%
• GTP-Binding Proteins 7%
• Psychological Inhibition 6%
• Sleep 5%
• Enzyme-Linked Immunosorbent Assay 5%
• Western Blotting 5%
• Lipids 4%
• Staining and Labeling 4%
• Cytokines 4%
• Kidney 4%
• In Vitro Techniques 3%
• Proteins 2%

Chemical Compounds

• Prostaglandin D2 97%
• Chemoattractant 17%
• Lipid 8%
• Protein 4%
• Molecule 4%