Histone gene expression in mammalian cells is codependent upon the Oct-1 transcription factor and its cognate, OCA-S coactivator complex. Surprisingly, GADPH plays an essential role in the OCA-S complex and confers redox dependence upon the in vitro transcription of histone genes.
|Original language||English (US)|
|Number of pages||3|
|State||Published - Jul 25 2003|
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)