TY - JOUR
T1 - Gender-based outcomes and acceptability of a computer-assisted psychosocial intervention for substance use disorders
AU - Campbell, Aimee N C
AU - Nunes, Edward V.
AU - Pavlicova, Martina
AU - Hatch-Maillette, Mary
AU - Hu, Mei Chen
AU - Bailey, Genie L.
AU - Sugarman, Dawn E.
AU - Miele, Gloria M.
AU - Rieckmann, Traci
AU - Shores-Wilson, Kathy
AU - Turrigiano, Eva
AU - Greenfield, Shelly F.
N1 - Funding Information:
Dr. Nunes has received medication for research studies from Alkermes/Cephalon, Duramed Pharmaceuticals, and Reckitt-Benckiser. Dr. Bailey's institution has received grant support from Titan Pharmaceuticals, Alkermes, BioDelivery Sciences International, and Orexo. Dr. Bailey has received travel support from Titan Pharmaceuticals and is on the advisory boards of Braeburn Pharmaceuticals, BioDelivery Sciences International, and Camurus AB. The other authors report no financial relationships with commercial interest. The authors wish to acknowledge the role of the research and clinical staff at the 10 recruitment sites, and gratitude for the time committed by the 507 participants.
Funding Information:
This work was supported by grants from the National Drug Abuse Treatment Clinical Trials Network (CTN), NIDA : U10 DA013035 (Edward V. Nunes and John Rotrosen), U10 DA015831 (Kathleen M. Carroll and Roger D. Weiss), U10 DA013034 (Maxine L. Stitzer and Robert P. Schwartz), U10 DA013720 (José Szapocznik and Lisa R. Metsch), U10 DA013732 (Teresa Winhusen), U10 DA020024 (Madhukar H. Trivedi), U10 DA013714 (Dennis M. Donovan and John Roll), U10 DA015815 (James L. Sorensen and Dennis McCarty), U10 DA013045 (Walter Ling), K24 DA022412 (Edward V. Nunes), and K24 DA019855 (Shelly F. Greenfield).
Publisher Copyright:
© 2015 Elsevier Inc.
PY - 2015/6/1
Y1 - 2015/6/1
N2 - Background: Digital technologies show promise for increasing treatment accessibility and improving quality of care, but little is known about gender differences. This secondary analysis uses data from a multi-site effectiveness trial of a computer-assisted behavioral intervention, conducted within NIDA's National Drug Abuse Clinical Trials Network, to explore gender differences in intervention acceptability and treatment outcomes. Methods: Men (n= 314) and women (n=192) were randomly assigned to 12-weeks of treatment-as-usual (TAU) or modified TAU. + Therapeutic Education System (TES), whereby TES substituted for 2. hours of TAU per week. TES is composed of 62 Web-delivered, multimedia modules, covering skills for achieving and maintaining abstinence plus prize-based incentives contingent on abstinence and treatment adherence. Outcomes were: (1) abstinence from drugs and heavy drinking in the last 4. weeks of treatment, (2) retention, (3) social functioning, and (4) drug and alcohol craving. Acceptability was the mean score across five indicators (i.e., interesting, useful, novel, easy to understand, and satisfaction). Results: Gender did not moderate the effect of treatment on any outcome. Women reported higher acceptability scores at week 4 (p= .02), but no gender differences were detected at weeks 8 or 12. Acceptability was positively associated with abstinence, but only among women (p= .01). Conclusions: Findings suggest that men and women derive similar benefits from participating in a computer-assisted intervention, a promising outcome as technology-based treatments expand. Acceptability was associated with abstinence outcomes among women. Future research should explore characteristics of women who report less satisfaction with this modality of treatment and ways to improve overall acceptability.
AB - Background: Digital technologies show promise for increasing treatment accessibility and improving quality of care, but little is known about gender differences. This secondary analysis uses data from a multi-site effectiveness trial of a computer-assisted behavioral intervention, conducted within NIDA's National Drug Abuse Clinical Trials Network, to explore gender differences in intervention acceptability and treatment outcomes. Methods: Men (n= 314) and women (n=192) were randomly assigned to 12-weeks of treatment-as-usual (TAU) or modified TAU. + Therapeutic Education System (TES), whereby TES substituted for 2. hours of TAU per week. TES is composed of 62 Web-delivered, multimedia modules, covering skills for achieving and maintaining abstinence plus prize-based incentives contingent on abstinence and treatment adherence. Outcomes were: (1) abstinence from drugs and heavy drinking in the last 4. weeks of treatment, (2) retention, (3) social functioning, and (4) drug and alcohol craving. Acceptability was the mean score across five indicators (i.e., interesting, useful, novel, easy to understand, and satisfaction). Results: Gender did not moderate the effect of treatment on any outcome. Women reported higher acceptability scores at week 4 (p= .02), but no gender differences were detected at weeks 8 or 12. Acceptability was positively associated with abstinence, but only among women (p= .01). Conclusions: Findings suggest that men and women derive similar benefits from participating in a computer-assisted intervention, a promising outcome as technology-based treatments expand. Acceptability was associated with abstinence outcomes among women. Future research should explore characteristics of women who report less satisfaction with this modality of treatment and ways to improve overall acceptability.
KW - Acceptability
KW - Computer-assisted treatment
KW - Gender differences
KW - Internet-delivered treatment
KW - Substance use disorders
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U2 - 10.1016/j.jsat.2014.12.006
DO - 10.1016/j.jsat.2014.12.006
M3 - Article
C2 - 25613105
AN - SCOPUS:84928761920
SN - 0740-5472
VL - 53
SP - 9
EP - 15
JO - Journal of Substance Abuse Treatment
JF - Journal of Substance Abuse Treatment
ER -